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Page 1
Aldosterone and cardiovascular disease.
Carey RM. Carey RM. Curr Opin Endocrinol Diabetes Obes. 2010 Jun;17(3):194-8. doi: 10.1097/med.0b013e3283390fa4. Curr Opin Endocrinol Diabetes Obes. 2010. PMID: 20422779 Review.
The sodium-bicarbonate cotransporter NBCe2 (slc4a5) expressed in human renal proximal tubules shows increased apical expression under high-salt conditions.
Gildea JJ, Xu P, Carlson JM, Gaglione RT, Bigler Wang D, Kemp BA, Reyes CM, McGrath HE, Carey RM, Jose PA, Felder RA. Gildea JJ, et al. Am J Physiol Regul Integr Comp Physiol. 2015 Dec 1;309(11):R1447-59. doi: 10.1152/ajpregu.00150.2015. Epub 2015 Oct 7. Am J Physiol Regul Integr Comp Physiol. 2015. PMID: 26447209 Free PMC article.
Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter.
Carey RM, Schoeffel CD, Gildea JJ, Jones JE, McGrath HE, Gordon LN, Park MJ, Sobota RS, Underwood PC, Williams J, Sun B, Raby B, Lasky-Su J, Hopkins PN, Adler GK, Williams SM, Jose PA, Felder RA. Carey RM, et al. Hypertension. 2012 Nov;60(5):1359-66. doi: 10.1161/HYPERTENSIONAHA.112.196071. Epub 2012 Sep 17. Hypertension. 2012. PMID: 22987918 Free PMC article. Clinical Trial.