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Impaired up-regulation of CD25 on CD4+ T cells in IFN-gamma knockout mice is associated with progression of myocarditis to heart failure.
Afanasyeva M, Georgakopoulos D, Belardi DF, Bedja D, Fairweather D, Wang Y, Kaya Z, Gabrielson KL, Rodriguez ER, Caturegli P, Kass DA, Rose NR. Afanasyeva M, et al. Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):180-5. doi: 10.1073/pnas.0408241102. Epub 2004 Dec 20. Proc Natl Acad Sci U S A. 2005. PMID: 15611472 Free PMC article.