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Structure-Based Design of Human TLR8-Specific Agonists with Augmented Potency and Adjuvanticity.
J Med Chem. 2015 Oct 8;58(19):7833-49. doi: 10.1021/acs.jmedchem.5b01087. Epub 2015 Sep 22.
J Med Chem. 2015.
PMID: 26351878
Free PMC article.
Identification of a Human Toll-Like Receptor (TLR) 8-Specific Agonist and a Functional Pan-TLR Inhibitor in 2-Aminoimidazoles.
Beesu M, Caruso G, Salyer AC, Shukla NM, Khetani KK, Smith LJ, Fox LM, Tanji H, Ohto U, Shimizu T, David SA.
Beesu M, et al.
J Med Chem. 2016 Apr 14;59(7):3311-30. doi: 10.1021/acs.jmedchem.6b00023. Epub 2016 Mar 22.
J Med Chem. 2016.
PMID: 26966993
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