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Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype.
Blasius AL, Dubin AE, Petrus MJ, Lim BK, Narezkina A, Criado JR, Wills DN, Xia Y, Moresco EM, Ehlers C, Knowlton KU, Patapoutian A, Beutler B. Blasius AL, et al. Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19413-8. doi: 10.1073/pnas.1117020108. Epub 2011 Nov 15. Proc Natl Acad Sci U S A. 2011. PMID: 22087007 Free PMC article.