GM076477/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2006	4
2007	4
2008	3
2009	7
2010	4
2011	4
2012	2
2013	3
2014	3
2015	4
2016	3
2017	4
2018	2
2024	0

1

Frontiers and opportunities in chemoenzymatic synthesis.

Mortison JD, Sherman DH. Mortison JD, et al. J Org Chem. 2010 Nov 5;75(21):7041-51. doi: 10.1021/jo101124n. J Org Chem. 2010. PMID: 20882949 Free PMC article. Review.

2

Architecture of the polyketide synthase module: surprises from electron cryo-microscopy.

Smith JL, Skiniotis G, Sherman DH. Smith JL, et al. Curr Opin Struct Biol. 2015 Apr;31:9-19. doi: 10.1016/j.sbi.2015.02.014. Epub 2015 Mar 16. Curr Opin Struct Biol. 2015. PMID: 25791608 Free PMC article. Review.

3

Developing tools for engineering hybrid polyketide synthetic pathways.

Kittendorf JD, Sherman DH. Kittendorf JD, et al. Curr Opin Biotechnol. 2006 Dec;17(6):597-605. doi: 10.1016/j.copbio.2006.09.005. Epub 2006 Oct 12. Curr Opin Biotechnol. 2006. PMID: 17046237 Review.

4

Structure of a modular polyketide synthase.

Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan AR, Håkansson K, Sherman DH, Smith JL, Skiniotis G. Dutta S, et al. Nature. 2014 Jun 26;510(7506):512-7. doi: 10.1038/nature13423. Epub 2014 Jun 18. Nature. 2014. PMID: 24965652 Free PMC article.

5

Automated genome mining for natural products.

Li MH, Ung PM, Zajkowski J, Garneau-Tsodikova S, Sherman DH. Li MH, et al. BMC Bioinformatics. 2009 Jun 16;10:185. doi: 10.1186/1471-2105-10-185. BMC Bioinformatics. 2009. PMID: 19531248 Free PMC article.

6

GNAT-like strategy for polyketide chain initiation.

Gu L, Geders TW, Wang B, Gerwick WH, Håkansson K, Smith JL, Sherman DH. Gu L, et al. Science. 2007 Nov 9;318(5852):970-4. doi: 10.1126/science.1148790. Science. 2007. PMID: 17991863

7

PKS-NRPS Enzymology and Structural Biology: Considerations in Protein Production.

Skiba MA, Maloney FP, Dan Q, Fraley AE, Aldrich CC, Smith JL, Brown WC. Skiba MA, et al. Methods Enzymol. 2018;604:45-88. doi: 10.1016/bs.mie.2018.01.035. Epub 2018 Mar 16. Methods Enzymol. 2018. PMID: 29779664 Free PMC article.

8

Substrate controlled divergence in polyketide synthase catalysis.

Hansen DA, Koch AA, Sherman DH. Hansen DA, et al. J Am Chem Soc. 2015 Mar 25;137(11):3735-8. doi: 10.1021/ja511743n. Epub 2015 Mar 12. J Am Chem Soc. 2015. PMID: 25730816 Free PMC article.

9

Structural basis for macrolactonization by the pikromycin thioesterase.

Akey DL, Kittendorf JD, Giraldes JW, Fecik RA, Sherman DH, Smith JL. Akey DL, et al. Nat Chem Biol. 2006 Oct;2(10):537-42. doi: 10.1038/nchembio824. Epub 2006 Sep 10. Nat Chem Biol. 2006. PMID: 16969372

10

Identification of a Thioesterase Bottleneck in the Pikromycin Pathway through Full-Module Processing of Unnatural Pentaketides.

Hansen DA, Koch AA, Sherman DH. Hansen DA, et al. J Am Chem Soc. 2017 Sep 27;139(38):13450-13455. doi: 10.1021/jacs.7b06432. Epub 2017 Sep 19. J Am Chem Soc. 2017. PMID: 28836772 Free PMC article.

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