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Insights into the substrate specificity of the MutT pyrophosphohydrolase using structural analogues of 8-oxo-2'-deoxyguanosine nucleotide.
Bioorg Med Chem Lett. 2016 Apr 15;26(8):2014-7. doi: 10.1016/j.bmcl.2016.02.083. Epub 2016 Mar 2.
Bioorg Med Chem Lett. 2016.
PMID: 26965860
Free PMC article.
YZGD from Paenibacillus thiaminolyticus, a pyridoxal phosphatase of the HAD (haloacid dehalogenase) superfamily and a versatile member of the Nudix (nucleoside diphosphate x) hydrolase superfamily.
Tirrell IM, Wall JL, Daley CJ, Denial SJ, Tennis FG, Galens KG, O'Handley SF.
Tirrell IM, et al.
Biochem J. 2006 Mar 15;394(Pt 3):665-74. doi: 10.1042/BJ20051172.
Biochem J. 2006.
PMID: 16336194
Free PMC article.
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