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ADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as transforming growth factor alpha, L-selectin, and tumor necrosis factor alpha.
Le Gall SM, Bobé P, Reiss K, Horiuchi K, Niu XD, Lundell D, Gibb DR, Conrad D, Saftig P, Blobel CP. Le Gall SM, et al. Mol Biol Cell. 2009 Mar;20(6):1785-94. doi: 10.1091/mbc.e08-11-1135. Epub 2009 Jan 21. Mol Biol Cell. 2009. PMID: 19158376 Free PMC article.