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Page 1
Shared genetic contribution to Ischaemic Stroke and Alzheimer's Disease.
Traylor M, Adib-Samii P, Harold D; Alzheimer's Disease Neuroimaging Initiative; International Stroke Genetics Consortium (ISGC), UK Young Lacunar Stroke DNA resource; Dichgans M, Williams J, Lewis CM, Markus HS; METASTROKE; International Genomics of Alzheimer's Project (IGAP), investigators. Traylor M, et al. Ann Neurol. 2016 May;79(5):739-747. doi: 10.1002/ana.24621. Epub 2016 Feb 23. Ann Neurol. 2016. PMID: 26913989 Free PMC article.
APOE ɛ2 is associated with white matter hyperintensity volume in CADASIL.
Gesierich B, Opherk C, Rosand J, Gonik M, Malik R, Jouvent E, Hervé D, Adib-Samii P, Bevan S, Pianese L, Silvestri S, Dotti MT, De Stefano N, van der Grond J, Boon EM, Pescini F, Rost N, Pantoni L, Oberstein SA, Federico A, Ragno M, Markus HS, Tournier-Lasserve E, Chabriat H, Dichgans M, Duering M, Ewers M. Gesierich B, et al. J Cereb Blood Flow Metab. 2016 Jan;36(1):199-203. doi: 10.1038/jcbfm.2015.85. J Cereb Blood Flow Metab. 2016. PMID: 25920955 Free PMC article.
Common NOTCH3 Variants and Cerebral Small-Vessel Disease.
Rutten-Jacobs LC, Traylor M, Adib-Samii P, Thijs V, Sudlow C, Rothwell PM, Boncoraglio G, Dichgans M, Bevan S, Meschia J, Levi C, Rost NS, Rosand J, Hassan A, Markus HS. Rutten-Jacobs LC, et al. Stroke. 2015 Jun;46(6):1482-7. doi: 10.1161/STROKEAHA.114.008540. Epub 2015 May 7. Stroke. 2015. PMID: 25953367 Free PMC article. Clinical Trial.
Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke.
Traylor M, Zhang CR, Adib-Samii P, Devan WJ, Parsons OE, Lanfranconi S, Gregory S, Cloonan L, Falcone GJ, Radmanesh F, Fitzpatrick K, Kanakis A, Barrick TR, Moynihan B, Lewis CM, Boncoraglio GB, Lemmens R, Thijs V, Sudlow C, Wardlaw J, Rothwell PM, Meschia JF, Worrall BB, Levi C, Bevan S, Furie KL, Dichgans M, Rosand J, Markus HS, Rost N; International Stroke Genetics Consortium. Traylor M, et al. Neurology. 2016 Jan 12;86(2):146-53. doi: 10.1212/WNL.0000000000002263. Epub 2015 Dec 16. Neurology. 2016. PMID: 26674333 Free PMC article.
Genome-wide genotyping demonstrates a polygenic risk score associated with white matter hyperintensity volume in CADASIL.
Opherk C, Gonik M, Duering M, Malik R, Jouvent E, Hervé D, Adib-Samii P, Bevan S, Pianese L, Silvestri S, Dotti MT, De Stefano N, Liem M, Boon EM, Pescini F, Pachai C, Bracoud L, Müller-Myhsok B, Meitinger T, Rost N, Pantoni L, Lesnik Oberstein S, Federico A, Ragno M, Markus HS, Tournier-Lasserve E, Rosand J, Chabriat H, Dichgans M. Opherk C, et al. Stroke. 2014 Apr;45(4):968-72. doi: 10.1161/STROKEAHA.113.004461. Epub 2014 Feb 27. Stroke. 2014. PMID: 24578207 Free article.
Genetic architecture of white matter hyperintensities differs in hypertensive and nonhypertensive ischemic stroke.
Adib-Samii P, Devan W, Traylor M, Lanfranconi S, Zhang CR, Cloonan L, Falcone GJ, Radmanesh F, Fitzpatrick K, Kanakis A, Rothwell PM, Sudlow C, Boncoraglio GB, Meschia JF, Levi C, Dichgans M, Bevan S, Rosand J, Rost NS, Markus HS. Adib-Samii P, et al. Stroke. 2015 Feb;46(2):348-53. doi: 10.1161/STROKEAHA.114.006849. Epub 2014 Dec 30. Stroke. 2015. PMID: 25550368 Free PMC article.
17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status.
Adib-Samii P, Rost N, Traylor M, Devan W, Biffi A, Lanfranconi S, Fitzpatrick K, Bevan S, Kanakis A, Valant V, Gschwendtner A, Malik R, Richie A, Gamble D, Segal H, Parati EA, Ciusani E, Holliday EG, Maguire J, Wardlaw J, Worrall B, Bis J, Wiggins KL, Longstreth W, Kittner SJ, Cheng YC, Mosley T, Falcone GJ, Furie KL, Leiva-Salinas C, Lau BC, Saleem Khan M; Australian Stroke Genetics Collaborative; Wellcome Trust Case-Control Consortium-2 (WTCCC2); METASTROKE; Sharma P, Fornage M, Mitchell BD, Psaty BM, Sudlow C, Levi C, Boncoraglio GB, Rothwell PM, Meschia J, Dichgans M, Rosand J, Markus HS; International Stroke Genetics Consortium. Adib-Samii P, et al. Stroke. 2013 Jun;44(6):1609-15. doi: 10.1161/STROKEAHA.113.679936. Epub 2013 May 14. Stroke. 2013. PMID: 23674528 Free PMC article.