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Anticancer properties of cannabidiol and Δ9-tetrahydrocannabinol and synergistic effects with gemcitabine and cisplatin in bladder cancer cell lines.
Whynot EG, Tomko AM, Dupré DJ. Whynot EG, et al. J Cannabis Res. 2023 Mar 4;5(1):7. doi: 10.1186/s42238-023-00174-z. J Cannabis Res. 2023. PMID: 36870996 Free PMC article.
INTRODUCTION: With the legalization of cannabis in multiple jurisdictions throughout the world, a larger proportion of the population consumes cannabis. Several studies have demonstrated anti-tumor effects of components present in cannabis in different models. ...Our in vi …
INTRODUCTION: With the legalization of cannabis in multiple jurisdictions throughout the world, a larger proportion of the population consum …
Anti-cancer properties of cannflavin A and potential synergistic effects with gemcitabine, cisplatin, and cannabinoids in bladder cancer.
Tomko AM, Whynot EG, Dupré DJ. Tomko AM, et al. J Cannabis Res. 2022 Jul 22;4(1):41. doi: 10.1186/s42238-022-00151-y. J Cannabis Res. 2022. PMID: 35869542 Free PMC article.
INTRODUCTION: Several studies have shown anti-tumor effects of components present in cannabis in different models. Unfortunately, little is known about the potential anti-tumoral effects of most compounds present in cannabis in bladder cancer and how these compounds could …
INTRODUCTION: Several studies have shown anti-tumor effects of components present in cannabis in different models. Unfortunately, lit …
The identification of dual protective agents against cisplatin-induced oto- and nephrotoxicity using the zebrafish model.
Wertman JN, Melong N, Stoyek MR, Piccolo O, Langley S, Orr B, Steele SL, Razaghi B, Berman JN. Wertman JN, et al. Elife. 2020 Jul 28;9:e56235. doi: 10.7554/eLife.56235. Elife. 2020. PMID: 32720645 Free PMC article.
Importantly, these compounds did not abrogate the cytotoxic effects of cisplatin on human cancer cells. This study provides insights into the mechanisms underlying cisplatin-induced oto- and nephrotoxicity and compelling preclinical evidence for the potential utility of do …
Importantly, these compounds did not abrogate the cytotoxic effects of cisplatin on human cancer cells. This study provides insights …
Attitudes of dental students in a Canadian university towards communication skills learning.
Ayn C, Robinson L, Matthews D, Andrews C. Ayn C, et al. Eur J Dent Educ. 2020 Feb;24(1):126-133. doi: 10.1111/eje.12476. Epub 2019 Nov 13. Eur J Dent Educ. 2020. PMID: 31643122
CS are imparted through the dental education experience, which can be optimised in part by incorporating student perceptions and needs into curricular development. The current study assessed student attitudes towards communication skills learning (CSL) in a Canadian univer …
CS are imparted through the dental education experience, which can be optimised in part by incorporating student perceptions and needs into …
Maternal pre-pregnancy weight status and health care use for mental health conditions in the offspring.
Grudzinski A, Campbell LA, Liu L, Brown MM, Dodds L, Kuhle S. Grudzinski A, et al. Eur Child Adolesc Psychiatry. 2019 Nov;28(11):1499-1506. doi: 10.1007/s00787-019-01312-w. Epub 2019 Mar 18. Eur Child Adolesc Psychiatry. 2019. PMID: 30887130
The objective of this study was to examine the relationship between pre-pregnancy maternal weight status and offspring physician visits for mental health conditions in childhood and adolescence. We conducted a population-based retrospective cohort study of singleton …
The objective of this study was to examine the relationship between pre-pregnancy maternal weight status and offspring physician visi …
Epigenetic patterns in Atlantic herring (Clupea harengus): Temperature and photoperiod as environmental stressors during larval development.
Kho J, Delgado ML, McCracken GR, Munden J, Ruzzante DE. Kho J, et al. Mol Ecol. 2024 Jan;33(1):e17187. doi: 10.1111/mec.17187. Epub 2023 Nov 1. Mol Ecol. 2024. PMID: 37909655
Temperature and photoperiod have been linked with spawning time and location in adult herring, but no study has thus far investigated the role of environmental factors on gene regulation during the vulnerable early developmental stages. ...
Temperature and photoperiod have been linked with spawning time and location in adult herring, but no study has thus far investigated …
Coherent long-term body-size responses across all Northwest Atlantic herring populations to warming and environmental change despite contrasting harvest and ecological factors.
Beaudry-Sylvestre M, Benoît HP, Hutchings JA. Beaudry-Sylvestre M, et al. Glob Chang Biol. 2024 Mar;30(3):e17187. doi: 10.1111/gcb.17187. Glob Chang Biol. 2024. PMID: 38456203
Temporal variation in residuals from this function was highly coherent among populations, further suggesting a common response to a large-scale environmental driver. The synchrony observed in this study system, despite strong differences in harvest and ecological histories …
Temporal variation in residuals from this function was highly coherent among populations, further suggesting a common response to a large-sc …