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Low-dose Btk inhibitors selectively block platelet activation by CLEC-2.
Haematologica. 2021 Jan 1;106(1):208-219. doi: 10.3324/haematol.2019.218545.
Haematologica. 2021.
PMID: 31949019
Free PMC article.
A rationale for blocking thromboinflammation in COVID-19 with Btk inhibitors.
Nicolson PL, Welsh JD, Chauhan A, Thomas MR, Kahn ML, Watson SP.
Nicolson PL, et al.
Platelets. 2020 Jul 3;31(5):685-690. doi: 10.1080/09537104.2020.1775189. Epub 2020 Jun 19.
Platelets. 2020.
PMID: 32552307
Free article.
No abstract available.
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Inhibition of Btk by Btk-specific concentrations of ibrutinib and acalabrutinib delays but does not block platelet aggregation mediated by glycoprotein VI.
Nicolson PLR, Hughes CE, Watson S, Nock SH, Hardy AT, Watson CN, Montague SJ, Clifford H, Huissoon AP, Malcor JD, Thomas MR, Pollitt AY, Tomlinson MG, Pratt G, Watson SP.
Nicolson PLR, et al.
Haematologica. 2018 Dec;103(12):2097-2108. doi: 10.3324/haematol.2018.193391. Epub 2018 Jul 19.
Haematologica. 2018.
PMID: 30026342
Free PMC article.
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