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Page 1
Translation stress and collided ribosomes are co-activators of cGAS.
Wan L, Juszkiewicz S, Blears D, Bajpe PK, Han Z, Faull P, Mitter R, Stewart A, Snijders AP, Hegde RS, Svejstrup JQ. Wan L, et al. Mol Cell. 2021 Jul 1;81(13):2808-2822.e10. doi: 10.1016/j.molcel.2021.05.018. Epub 2021 Jun 9. Mol Cell. 2021. PMID: 34111399 Free PMC article.
DNA-directed termination of RNA polymerase II transcription.
Han Z, Moore GA, Mitter R, Lopez Martinez D, Wan L, Dirac Svejstrup AB, Rueda DS, Svejstrup JQ. Han Z, et al. Mol Cell. 2023 Sep 21;83(18):3253-3267.e7. doi: 10.1016/j.molcel.2023.08.007. Epub 2023 Sep 7. Mol Cell. 2023. PMID: 37683646 Free PMC article.
Regulation of the RNAPII Pool Is Integral to the DNA Damage Response.
Tufegdžić Vidaković A, Mitter R, Kelly GP, Neumann M, Harreman M, Rodríguez-Martínez M, Herlihy A, Weems JC, Boeing S, Encheva V, Gaul L, Milligan L, Tollervey D, Conaway RC, Conaway JW, Snijders AP, Stewart A, Svejstrup JQ. Tufegdžić Vidaković A, et al. Cell. 2020 Mar 19;180(6):1245-1261.e21. doi: 10.1016/j.cell.2020.02.009. Epub 2020 Mar 5. Cell. 2020. PMID: 32142654 Free PMC article.
SCAF4 and SCAF8, mRNA Anti-Terminator Proteins.
Gregersen LH, Mitter R, Ugalde AP, Nojima T, Proudfoot NJ, Agami R, Stewart A, Svejstrup JQ. Gregersen LH, et al. Cell. 2019 Jun 13;177(7):1797-1813.e18. doi: 10.1016/j.cell.2019.04.038. Epub 2019 May 16. Cell. 2019. PMID: 31104839 Free PMC article.
Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response.
Mulderrig L, Garaycoechea JI, Tuong ZK, Millington CL, Dingler FA, Ferdinand JR, Gaul L, Tadross JA, Arends MJ, O'Rahilly S, Crossan GP, Clatworthy MR, Patel KJ. Mulderrig L, et al. Nature. 2021 Dec;600(7887):158-163. doi: 10.1038/s41586-021-04133-7. Epub 2021 Nov 24. Nature. 2021. PMID: 34819667
The ASC-1 Complex Disassembles Collided Ribosomes.
Juszkiewicz S, Speldewinde SH, Wan L, Svejstrup JQ, Hegde RS. Juszkiewicz S, et al. Mol Cell. 2020 Aug 20;79(4):603-614.e8. doi: 10.1016/j.molcel.2020.06.006. Epub 2020 Jun 23. Mol Cell. 2020. PMID: 32579943 Free PMC article.
Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability.
Geijer ME, Zhou D, Selvam K, Steurer B, Mukherjee C, Evers B, Cugusi S, van Toorn M, van der Woude M, Janssens RC, Kok YP, Gong W, Raams A, Lo CSY, Lebbink JHG, Geverts B, Plummer DA, Bezstarosti K, Theil AF, Mitter R, Houtsmuller AB, Vermeulen W, Demmers JAA, Li S, van Vugt MATM, Lans H, Bernards R, Svejstrup JQ, Ray Chaudhuri A, Wyrick JJ, Marteijn JA. Geijer ME, et al. Nat Cell Biol. 2021 Jun;23(6):608-619. doi: 10.1038/s41556-021-00692-z. Epub 2021 Jun 9. Nat Cell Biol. 2021. PMID: 34108662 Free PMC article.
21 results