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2007 | 2 |
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Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit.
Antimicrob Agents Chemother. 2007 Dec;51(12):4462-5. doi: 10.1128/AAC.00455-07. Epub 2007 Jul 30.
Antimicrob Agents Chemother. 2007.
PMID: 17664317
Free PMC article.
The structures of antibiotics bound to the E site region of the 50 S ribosomal subunit of Haloarcula marismortui: 13-deoxytedanolide and girodazole.
Schroeder SJ, Blaha G, Tirado-Rives J, Steitz TA, Moore PB.
Schroeder SJ, et al.
J Mol Biol. 2007 Apr 13;367(5):1471-9. doi: 10.1016/j.jmb.2007.01.081. Epub 2007 Feb 7.
J Mol Biol. 2007.
PMID: 17321546
Free PMC article.
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Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
Blaha G, Gürel G, Schroeder SJ, Moore PB, Steitz TA.
Blaha G, et al.
J Mol Biol. 2008 Jun 6;379(3):505-19. doi: 10.1016/j.jmb.2008.03.075. Epub 2008 Apr 8.
J Mol Biol. 2008.
PMID: 18455733
Free PMC article.
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