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The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus.
J Clin Invest. 2002 Jan;109(1):121-30. doi: 10.1172/JCI14080.
J Clin Invest. 2002.
PMID: 11781357
Free PMC article.
A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.
Finck BN, Han X, Courtois M, Aimond F, Nerbonne JM, Kovacs A, Gross RW, Kelly DP.
Finck BN, et al.
Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1226-31. doi: 10.1073/pnas.0336724100. Epub 2003 Jan 27.
Proc Natl Acad Sci U S A. 2003.
PMID: 12552126
Free PMC article.
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