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Intestinal transgene delivery with native E. coli chassis allows persistent physiological changes.
Russell BJ, Brown SD, Siguenza N, Mai I, Saran AR, Lingaraju A, Maissy ES, Dantas Machado AC, Pinto AFM, Sanchez C, Rossitto LA, Miyamoto Y, Richter RA, Ho SB, Eckmann L, Hasty J, Gonzalez DJ, Saghatelian A, Knight R, Zarrinpar A. Russell BJ, et al. Cell. 2022 Aug 18;185(17):3263-3277.e15. doi: 10.1016/j.cell.2022.06.050. Epub 2022 Aug 4. Cell. 2022. PMID: 35931082 Free PMC article.