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Modulation of antigen delivery and lymph node activation in nonhuman primates by saponin adjuvant saponin/monophosphoryl lipid A nanoparticle.
Yousefpour P, Zhang YJ, Maiorino L, Melo MB, Arainga Ramirez MA, Kumarapperuma SC, Xiao P, Silva M, Li N, Michaels KK, Georgeson E, Eskandarzadeh S, Kubitz M, Groschel B, Qureshi K, Fontenot J, Hangartner L, Nedellec R, Love JC, Burton DR, Schief WR, Villinger FJ, Irvine DJ. Yousefpour P, et al. PNAS Nexus. 2024 Nov 25;3(12):pgae529. doi: 10.1093/pnasnexus/pgae529. eCollection 2024 Dec. PNAS Nexus. 2024. PMID: 39677368 Free PMC article.
Vaccines combining slow delivery and follicle targeting of antigens increase germinal center B cell clonal diversity and clonal expansion.
Rodrigues KA, Zhang YJ, Aung A, Morgan DM, Maiorino L, Yousefpour P, Gibson G, Ozorowski G, Gregory JR, Amlashi P, Buckley M, Ward AB, Schief WR, Love JC, Irvine DJ. Rodrigues KA, et al. bioRxiv [Preprint]. 2024 Aug 19:2024.08.19.608655. doi: 10.1101/2024.08.19.608655. bioRxiv. 2024. PMID: 39229011 Free PMC article. Preprint.