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Bispecific antibody shuttles targeting CD98hc mediate efficient and long-lived brain delivery of IgGs.
Pornnoppadol G, Bond LG, Lucas MJ, Zupancic JM, Kuo YH, Zhang B, Greineder CF, Tessier PM. Pornnoppadol G, et al. bioRxiv [Preprint]. 2023 Apr 29:2023.04.29.538811. doi: 10.1101/2023.04.29.538811. bioRxiv. 2023. Update in: Cell Chem Biol. 2024 Feb 15;31(2):361-372.e8. doi: 10.1016/j.chembiol.2023.09.008 PMID: 37162883 Free PMC article. Updated. Preprint.