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Inactivation of the Hippo tumor suppressor pathway promotes melanoma.
Vittoria MA, Kingston N, Kotynkova K, Xia E, Hong R, Huang L, McDonald S, Tilston-Lunel A, Darp R, Campbell JD, Lang D, Xu X, Ceol CJ, Varelas X, Ganem NJ. Vittoria MA, et al. Nat Commun. 2022 Jun 29;13(1):3732. doi: 10.1038/s41467-022-31399-w. Nat Commun. 2022. PMID: 35768444 Free PMC article.
Aberrant epithelial polarity cues drive the development of precancerous airway lesions.
Tilston-Lunel A, Mazzilli S, Kingston NM, Szymaniak AD, Hicks-Berthet J, Kern JG, Abo K, Reid ME, Perdomo C, Wilson AA, Spira A, Beane J, Varelas X. Tilston-Lunel A, et al. Proc Natl Acad Sci U S A. 2021 May 4;118(18):e2019282118. doi: 10.1073/pnas.2019282118. Proc Natl Acad Sci U S A. 2021. PMID: 33903236 Free PMC article.