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Id2 reinforces TH1 differentiation and inhibits E2A to repress TFH differentiation.

Shaw LA, Bélanger S, Omilusik KD, Cho S, Scott-Browne JP, Nance JP, Goulding J, Lasorella A, Lu LF, Crotty S, Goldrath AW. Shaw LA, et al. Nat Immunol. 2016 Jul;17(7):834-43. doi: 10.1038/ni.3461. Epub 2016 May 23. Nat Immunol. 2016. PMID: 27213691 Free PMC article.

Ubiquitin Specific Protease 1 Expression and Function in T Cell Immunity.

Omilusik KD, Nadjsombati MS, Yoshida TM, Shaw LA, Goulding J, Goldrath AW. Omilusik KD, et al. J Immunol. 2021 Sep 1;207(5):1377-1387. doi: 10.4049/jimmunol.2100303. Epub 2021 Aug 11. J Immunol. 2021. PMID: 34380645 Free PMC article.

Sustained Id2 regulation of E proteins is required for terminal differentiation of effector CD8⁺ T cells.

Omilusik KD, Nadjsombati MS, Shaw LA, Yu B, Milner JJ, Goldrath AW. Omilusik KD, et al. J Exp Med. 2018 Mar 5;215(3):773-783. doi: 10.1084/jem.20171584. Epub 2018 Feb 12. J Exp Med. 2018. PMID: 29440362 Free PMC article.

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