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Phosphomimetic substitutions in TDP-43's transiently α-helical region suppress phase separation.
Biophys J. 2024 Feb 6;123(3):361-373. doi: 10.1016/j.bpj.2024.01.001. Epub 2024 Jan 4.
Biophys J. 2024.
PMID: 38178578
Free article.
Pathological C-terminal phosphomimetic substitutions alter the mechanism of liquid-liquid phase separation of TDP-43 low complexity domain.
Haider R, Shipley B, Surewicz K, Hinczewski M, Surewicz WK.
Haider R, et al.
Protein Sci. 2024 Oct;33(10):e5179. doi: 10.1002/pro.5179.
Protein Sci. 2024.
PMID: 39302099
Free PMC article.
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