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Exosome-mediated delivery of siRNA in vitro and in vivo.
El-Andaloussi S, Lee Y, Lakhal-Littleton S, Li J, Seow Y, Gardiner C, Alvarez-Erviti L, Sargent IL, Wood MJ. El-Andaloussi S, et al. Nat Protoc. 2012 Dec;7(12):2112-26. doi: 10.1038/nprot.2012.131. Epub 2012 Nov 15. Nat Protoc. 2012. PMID: 23154783
DJ-1 is a redox sensitive adapter protein for high molecular weight complexes involved in regulation of catecholamine homeostasis.
Piston D, Alvarez-Erviti L, Bansal V, Gargano D, Yao Z, Szabadkai G, Odell M, Puno MR, Björkblom B, Maple-Grødem J, Breuer P, Kaut O, Larsen JP, Bonn S, Møller SG, Wüllner U, Schapira AHV, Gegg ME. Piston D, et al. Hum Mol Genet. 2018 Feb 1;27(3):576. doi: 10.1093/hmg/ddx425. Hum Mol Genet. 2018. PMID: 29309579 Free PMC article. No abstract available.
Systemic Exosomal Delivery of shRNA Minicircles Prevents Parkinsonian Pathology.
Izco M, Blesa J, Schleef M, Schmeer M, Porcari R, Al-Shawi R, Ellmerich S, de Toro M, Gardiner C, Seow Y, Reinares-Sebastian A, Forcen R, Simons JP, Bellotti V, Cooper JM, Alvarez-Erviti L. Izco M, et al. Mol Ther. 2019 Dec 4;27(12):2111-2122. doi: 10.1016/j.ymthe.2019.08.010. Epub 2019 Aug 27. Mol Ther. 2019. PMID: 31501034 Free PMC article.