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Drusen complement components C3a and C5a promote choroidal neovascularization.
Nozaki M, Raisler BJ, Sakurai E, Sarma JV, Barnum SR, Lambris JD, Chen Y, Zhang K, Ambati BK, Baffi JZ, Ambati J. Nozaki M, et al. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2328-33. doi: 10.1073/pnas.0408835103. Epub 2006 Feb 1. Proc Natl Acad Sci U S A. 2006. PMID: 16452172 Free PMC article.
Toward a higher fidelity model of AMD.
Raisler BJ, Nozaki M, Baffi J, Hauswirth WW, Ambati J. Raisler BJ, et al. Adv Exp Med Biol. 2008;613:185-92. doi: 10.1007/978-0-387-74904-4_21. Adv Exp Med Biol. 2008. PMID: 18188944 No abstract available.