DA 13449/DA/NIDA NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2001	1
2002	5
2003	5
2004	2
2005	5
2006	3
2007	2
2008	3
2009	4
2010	3
2011	3
2012	1
2013	2
2015	2
2016	1
2025	0

1

Plasmon resonance methods in GPCR signaling and other membrane events.

Alves ID, Park CK, Hruby VJ. Alves ID, et al. Curr Protein Pept Sci. 2005 Aug;6(4):293-312. doi: 10.2174/1389203054546352. Curr Protein Pept Sci. 2005. PMID: 16101432 Free PMC article. Review.

2

Design of novel melanotropin agonists and antagonists with high potency and selectivity for human melanocortin receptors.

Cai M, Mayorov AV, Ying J, Stankova M, Trivedi D, Cabello C, Hruby VJ. Cai M, et al. Peptides. 2005 Aug;26(8):1481-5. doi: 10.1016/j.peptides.2005.03.020. Peptides. 2005. PMID: 15876475 Review.

3

Techniques: plasmon-waveguide resonance (PWR) spectroscopy as a tool to study ligand-GPCR interactions.

Tollin G, Salamon Z, Hruby VJ. Tollin G, et al. Trends Pharmacol Sci. 2003 Dec;24(12):655-9. doi: 10.1016/j.tips.2003.10.010. Trends Pharmacol Sci. 2003. PMID: 14654307 Review.

4

Synthesis and activity of endomorphin-2 and morphiceptin analogues with proline surrogates in position 2.

Giordano C, Sansone A, Masi A, Lucente G, Punzi P, Mollica A, Pinnen F, Feliciani F, Cacciatore I, Davis P, Lai J, Ma SW, Porreca F, Hruby V. Giordano C, et al. Eur J Med Chem. 2010 Oct;45(10):4594-600. doi: 10.1016/j.ejmech.2010.07.022. Epub 2010 Jul 21. Eur J Med Chem. 2010. PMID: 20692738 Free PMC article.

5

Design synthesis and structure-activity relationship of 5-substituted (tetrahydronaphthalen-2yl)methyl with N-phenyl-N-(piperidin-2-yl)propionamide derivatives as opioid ligands.

Deekonda S, Rankin D, Davis P, Lai J, Vanderah TW, Porecca F, Hruby VJ. Deekonda S, et al. Bioorg Med Chem. 2016 Jan 15;24(2):85-91. doi: 10.1016/j.bmc.2015.11.030. Epub 2015 Nov 23. Bioorg Med Chem. 2016. PMID: 26712115 Free PMC article.

6

Development of potent μ and δ opioid agonists with high lipophilicity.

Lee YS, Kulkarani V, Cowell SM, Ma SW, Davis P, Hanlon KE, Vanderah TW, Lai J, Porreca F, Vardanyan R, Hruby VJ. Lee YS, et al. J Med Chem. 2011 Jan 13;54(1):382-6. doi: 10.1021/jm100982d. Epub 2010 Dec 3. J Med Chem. 2011. PMID: 21128594 Free PMC article.

7

Design, synthesis, and biological evaluation of novel bifunctional C-terminal-modified peptides for delta/mu opioid receptor agonists and neurokinin-1 receptor antagonists.

Yamamoto T, Nair P, Davis P, Ma SW, Navratilova E, Moye S, Tumati S, Lai J, Vanderah TW, Yamamura HI, Porreca F, Hruby VJ. Yamamoto T, et al. J Med Chem. 2007 Jun 14;50(12):2779-86. doi: 10.1021/jm061369n. Epub 2007 May 22. J Med Chem. 2007. PMID: 17516639 Free PMC article.

8

Direct observation of G-protein binding to the human delta-opioid receptor using plasmon-waveguide resonance spectroscopy.

Alves ID, Salamon Z, Varga E, Yamamura HI, Tollin G, Hruby VJ. Alves ID, et al. J Biol Chem. 2003 Dec 5;278(49):48890-7. doi: 10.1074/jbc.M306866200. Epub 2003 Sep 30. J Biol Chem. 2003. PMID: 14522991 Free article.

9

Building a better analgesic: multifunctional compounds that address injury-induced pathology to enhance analgesic efficacy while eliminating unwanted side effects.

Largent-Milnes TM, Brookshire SW, Skinner DP Jr, Hanlon KE, Giuvelis D, Yamamoto T, Davis P, Campos CR, Nair P, Deekonda S, Bilsky EJ, Porreca F, Hruby VJ, Vanderah TW. Largent-Milnes TM, et al. J Pharmacol Exp Ther. 2013 Oct;347(1):7-19. doi: 10.1124/jpet.113.205245. Epub 2013 Jul 16. J Pharmacol Exp Ther. 2013. PMID: 23860305 Free PMC article.

10

Novel 3D pharmacophore of alpha-MSH/gamma-MSH hybrids leads to selective human MC1R and MC3R analogues.

Cai M, Mayorov AV, Cabello C, Stankova M, Trivedi D, Hruby VJ. Cai M, et al. J Med Chem. 2005 Mar 24;48(6):1839-48. doi: 10.1021/jm049579s. J Med Chem. 2005. PMID: 15771429

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