CA40090/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
1986	2
1987	2
1988	2
1989	2
1990	4
1991	5
1992	2
1993	5
1996	2
1997	1
1999	1
2001	1
2002	1
2025	0

1

Intercalator-induced, topoisomerase II-mediated DNA cleavage and its modification by antineoplastic antimetabolites.

Zwelling LA, Silberman L, Estey E. Zwelling LA, et al. Int J Radiat Oncol Biol Phys. 1986 Jul;12(7):1041-7. doi: 10.1016/0360-3016(86)90222-1. Int J Radiat Oncol Biol Phys. 1986. PMID: 2427489 Review.

2

Effect of 1-beta-D-arabinofuranosylcytosine (ara-C) on nuclear topoisomerase II activity and on the DNA cleavage and cytotoxicity produced by 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) and etoposide in m-AMSA-sensitive and -resistant human leukemia cells.

Bakic M, Chan D, Andersson BS, Beran M, Silberman L, Estey E, Ricketts L, Zwelling LA. Bakic M, et al. Biochem Pharmacol. 1987 Dec 1;36(23):4067-77. doi: 10.1016/0006-2952(87)90563-6. Biochem Pharmacol. 1987. PMID: 2825713

3

Enhanced etoposide sensitivity following adenovirus-mediated human topoisomerase IIalpha gene transfer is independent of topoisomerase IIbeta.

Zhou Z, Zwelling LA, Ganapathi R, Kleinerman ES. Zhou Z, et al. Br J Cancer. 2001 Sep 1;85(5):747-51. doi: 10.1054/bjoc.2001.1966. Br J Cancer. 2001. PMID: 11531262 Free PMC article.

4

Adenovirus-mediated human topoisomerase IIalpha gene transfer increases the sensitivity of etoposide-resistant human breast cancer cells.

Zhou Z, Zwelling LA, Kawakami Y, An T, Kobayashi K, Herzog C, Kleinerman ES. Zhou Z, et al. Cancer Res. 1999 Sep 15;59(18):4618-24. Cancer Res. 1999. PMID: 10493516

5

Cross-resistance of an amsacrine-resistant human leukemia line to topoisomerase II reactive DNA intercalating agents. Evidence for two topoisomerase II directed drug actions.

Zwelling LA, Mayes J, Hinds M, Chan D, Altschuler E, Carroll B, Parker E, Deisseroth K, Radcliffe A, Seligman M, et al. Zwelling LA, et al. Biochemistry. 1991 Apr 23;30(16):4048-55. doi: 10.1021/bi00230a032. Biochemistry. 1991. PMID: 1850298

6

Phase I clinical and plasma and cellular pharmacological study of topotecan without and with granulocyte colony-stimulating factor.

Abbruzzese JL, Madden T, Sugarman SM, Ellis AL, Loughlin S, Hess KR, Newman RA, Zwelling LA, Raber MN. Abbruzzese JL, et al. Clin Cancer Res. 1996 Sep;2(9):1489-97. Clin Cancer Res. 1996. PMID: 9816325 Clinical Trial.

7

A restriction fragment length polymorphism for human topoisomerase II: possible relationship to drug-resistance.

Zwelling LA, Mayes J, Deisseroth K, Hinds M, Grant G, Pathak S, Ledley FD, Vyas R, Hittelman W. Zwelling LA, et al. Cancer Commun. 1990;2(11):357-61. doi: 10.3727/095535490820874047. Cancer Commun. 1990. PMID: 1978687

8

Components of intrinsic drug resistance in the rat hepatoma.

Ellis AL, Munger CE, Bunch RT, Woods KE, Randolph JK, Boise L, Swerdlow PS, Zwelling LA, Hinds M, Yanovich S, et al. Ellis AL, et al. Biochem Pharmacol. 1992 Jan 22;43(2):331-42. doi: 10.1016/0006-2952(92)90296-u. Biochem Pharmacol. 1992. PMID: 1310853

9

Altered phosphorylation, biosynthesis and degradation of the 170 kDa isoform of topoisomerase II in amsacrine-resistant human leukemia cells.

Ganapathi R, Zwelling L, Constantinou A, Ford J, Grabowski D. Ganapathi R, et al. Biochem Biophys Res Commun. 1993 May 14;192(3):1274-80. doi: 10.1006/bbrc.1993.1554. Biochem Biophys Res Commun. 1993. PMID: 8389546

10

Characterization of an amsacrine-resistant line of human leukemia cells. Evidence for a drug-resistant form of topoisomerase II.

Zwelling LA, Hinds M, Chan D, Mayes J, Sie KL, Parker E, Silberman L, Radcliffe A, Beran M, Blick M. Zwelling LA, et al. J Biol Chem. 1989 Oct 5;264(28):16411-20. J Biol Chem. 1989. PMID: 2550442 Free article.

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