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DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome.
Samir P, Kesavardhana S, Patmore DM, Gingras S, Malireddi RKS, Karki R, Guy CS, Briard B, Place DE, Bhattacharya A, Sharma BR, Nourse A, King SV, Pitre A, Burton AR, Pelletier S, Gilbertson RJ, Kanneganti TD. Samir P, et al. Nature. 2019 Sep;573(7775):590-594. doi: 10.1038/s41586-019-1551-2. Epub 2019 Sep 11. Nature. 2019. PMID: 31511697 Free PMC article.