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A gene therapy targeting medium-chain acyl-CoA dehydrogenase (MCAD) did not protect against diabetes-induced cardiac pathology.
Weeks KL, Kiriazis H, Wadley GD, Masterman EI, Sergienko NM, Raaijmakers AJA, Trewin AJ, Harmawan CA, Yildiz GS, Liu Y, Drew BG, Gregorevic P, Delbridge LMD, McMullen JR, Bernardo BC. Weeks KL, et al. J Mol Med (Berl). 2024 Jan;102(1):95-111. doi: 10.1007/s00109-023-02397-2. Epub 2023 Nov 21. J Mol Med (Berl). 2024. PMID: 37987775
Results of an Australian trial of an automated insulin delivery (AID) system and other studies support likely benefit of AID use for many Australian adults with type 1 diabetes.
Jenkins AJ, Januszewski AS, Kirby A, Hendrieckx C, McAuley SA, Lee MH, Paldus B, Vogrin S, de Bock MI, Abraham MB, Bach LA, Burt MG, Cohen ND, Colman PG, Davis EA, Holmes-Walker DJ, Kaye J, Keech AC, Kumareswaran K, MacIsaac RJ, McCallum RW, Sims CM, Speight J, Stranks SN, Sundararajan V, Trawley S, Ward GM, Jones TW, O'Neal DN; Australian JDRF Closed Loop Research Group. Jenkins AJ, et al. Intern Med J. 2024 Nov 27. doi: 10.1111/imj.16567. Online ahead of print. Intern Med J. 2024. PMID: 39601386