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3D structures of the Plasmodium vivax subtilisin-like drug target SUB1 reveal conformational changes to accommodate a substrate-derived α-ketoamide inhibitor.
Martinez M, Batista FA, Maurel M, Bouillon A, Ortega Varga L, Wehenkel AM, Le Chevalier-Sontag L, Blondel A, Haouz A, Hernandez JF, Alzari PM, Barale JC. Martinez M, et al. Acta Crystallogr D Struct Biol. 2023 Aug 1;79(Pt 8):721-734. doi: 10.1107/S2059798323004710. Epub 2023 Jul 10. Acta Crystallogr D Struct Biol. 2023. PMID: 37428845