AI070721/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2007	1
2009	2
2010	3
2011	2
2012	2
2013	1
2014	2
2016	1
2018	1
2025	0

1

Replacing sulfa drugs with novel DHPS inhibitors.

Hammoudeh DI, Zhao Y, White SW, Lee RE. Hammoudeh DI, et al. Future Med Chem. 2013 Jul;5(11):1331-40. doi: 10.4155/fmc.13.97. Future Med Chem. 2013. PMID: 23859210 Free PMC article. Review.

2

Development of a pterin-based fluorescent probe for screening dihydropteroate synthase.

Zhao Y, Hammoudeh D, Lin W, Das S, Yun MK, Li Z, Griffith E, Chen T, White SW, Lee RE. Zhao Y, et al. Bioconjug Chem. 2011 Oct 19;22(10):2110-7. doi: 10.1021/bc200346e. Epub 2011 Sep 30. Bioconjug Chem. 2011. PMID: 21916405 Free PMC article.

3

Catalysis and sulfa drug resistance in dihydropteroate synthase.

Yun MK, Wu Y, Li Z, Zhao Y, Waddell MB, Ferreira AM, Lee RE, Bashford D, White SW. Yun MK, et al. Science. 2012 Mar 2;335(6072):1110-4. doi: 10.1126/science.1214641. Science. 2012. PMID: 22383850 Free PMC article.

4

Structural studies of pterin-based inhibitors of dihydropteroate synthase.

Hevener KE, Yun MK, Qi J, Kerr ID, Babaoglu K, Hurdle JG, Balakrishna K, White SW, Lee RE. Hevener KE, et al. J Med Chem. 2010 Jan 14;53(1):166-77. doi: 10.1021/jm900861d. J Med Chem. 2010. PMID: 19899766 Free PMC article.

5

Validation of molecular docking programs for virtual screening against dihydropteroate synthase.

Hevener KE, Zhao W, Ball DM, Babaoglu K, Qi J, White SW, Lee RE. Hevener KE, et al. J Chem Inf Model. 2009 Feb;49(2):444-60. doi: 10.1021/ci800293n. J Chem Inf Model. 2009. PMID: 19434845 Free PMC article.

6

A statistical framework to evaluate virtual screening.

Zhao W, Hevener KE, White SW, Lee RE, Boyett JM. Zhao W, et al. BMC Bioinformatics. 2009 Jul 20;10:225. doi: 10.1186/1471-2105-10-225. BMC Bioinformatics. 2009. PMID: 19619306 Free PMC article.

7

Structure-based design of novel pyrimido[4,5-c]pyridazine derivatives as dihydropteroate synthase inhibitors with increased affinity.

Zhao Y, Hammoudeh D, Yun MK, Qi J, White SW, Lee RE. Zhao Y, et al. ChemMedChem. 2012 May;7(5):861-70. doi: 10.1002/cmdc.201200049. Epub 2012 Mar 13. ChemMedChem. 2012. PMID: 22416048 Free PMC article.

8

Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents.

Zhao Y, Shadrick WR, Wallace MJ, Wu Y, Griffith EC, Qi J, Yun MK, White SW, Lee RE. Zhao Y, et al. Bioorg Med Chem Lett. 2016 Aug 15;26(16):3950-4. doi: 10.1016/j.bmcl.2016.07.006. Epub 2016 Jul 4. Bioorg Med Chem Lett. 2016. PMID: 27423480 Free PMC article.

9

The Structural and Functional Basis for Recurring Sulfa Drug Resistance Mutations in Staphylococcus aureus Dihydropteroate Synthase.

Griffith EC, Wallace MJ, Wu Y, Kumar G, Gajewski S, Jackson P, Phelps GA, Zheng Z, Rock CO, Lee RE, White SW. Griffith EC, et al. Front Microbiol. 2018 Jul 17;9:1369. doi: 10.3389/fmicb.2018.01369. eCollection 2018. Front Microbiol. 2018. PMID: 30065703 Free PMC article.

10

Identification and characterization of an allosteric inhibitory site on dihydropteroate synthase.

Hammoudeh DI, Daté M, Yun MK, Zhang W, Boyd VA, Viacava Follis A, Griffith E, Lee RE, Bashford D, White SW. Hammoudeh DI, et al. ACS Chem Biol. 2014 Jun 20;9(6):1294-302. doi: 10.1021/cb500038g. Epub 2014 Mar 27. ACS Chem Biol. 2014. PMID: 24650357 Free PMC article.

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