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Pocket 4 of the HLA-DR(alpha,beta 1*0401) molecule is a major determinant of T cells recognition of peptide.
J Exp Med. 1995 Mar 1;181(3):915-26. doi: 10.1084/jem.181.3.915.
J Exp Med. 1995.
PMID: 7869051
Free PMC article.
Negatively charged residues interacting with the p4 pocket confer binding specificity to DRB1*0401.
Woulfe SL, Bono CP, Zacheis ML, Kirschmann DA, Baudino TA, Swearingen C, Karr RW, Schwartz BD.
Woulfe SL, et al.
Arthritis Rheum. 1995 Dec;38(12):1744-53. doi: 10.1002/art.1780381207.
Arthritis Rheum. 1995.
PMID: 8849346
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