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Applying the new genomics to alcohol dependence.
Farris SP, Pietrzykowski AZ, Miles MF, O'Brien MA, Sanna PP, Zakhari S, Mayfield RD, Harris RA. Farris SP, et al. Alcohol. 2015 Dec;49(8):825-36. doi: 10.1016/j.alcohol.2015.03.001. Epub 2015 Mar 28. Alcohol. 2015. PMID: 25896098 Free PMC article. Review.
MeCP2 regulates ethanol sensitivity and intake.
Repunte-Canonigo V, Chen J, Lefebvre C, Kawamura T, Kreifeldt M, Basson O, Roberts AJ, Sanna PP. Repunte-Canonigo V, et al. Addict Biol. 2014 Sep;19(5):791-9. doi: 10.1111/adb.12047. Epub 2013 Feb 28. Addict Biol. 2014. PMID: 23448145 Free PMC article.
Nf1 regulates alcohol dependence-associated excessive drinking and gamma-aminobutyric acid release in the central amygdala in mice and is associated with alcohol dependence in humans.
Repunte-Canonigo V, Herman M, Kawamura T, Kranzler HR, Sherva R, Gelernter J, Farrer LA, Roberto M, Sanna PP. Repunte-Canonigo V, et al. Biol Psychiatry. 2015 May 15;77(10):870-879. doi: 10.1016/j.biopsych.2014.07.031. Epub 2014 Aug 19. Biol Psychiatry. 2015. PMID: 25483400 Free PMC article.