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Page 1
cfDNA methylome profiling for detection and subtyping of small cell lung cancers.
Chemi F, Pearce SP, Clipson A, Hill SM, Conway AM, Richardson SA, Kamieniecka K, Caeser R, White DJ, Mohan S, Foy V, Simpson KL, Galvin M, Frese KK, Priest L, Egger J, Kerr A, Massion PP, Poirier JT, Brady G, Blackhall F, Rothwell DG, Rudin CM, Dive C. Chemi F, et al. Nat Cancer. 2022 Oct;3(10):1260-1270. doi: 10.1038/s43018-022-00415-9. Epub 2022 Aug 8. Nat Cancer. 2022. PMID: 35941262 Free PMC article.
Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.
Arce Vargas F, Furness AJS, Litchfield K, Joshi K, Rosenthal R, Ghorani E, Solomon I, Lesko MH, Ruef N, Roddie C, Henry JY, Spain L, Ben Aissa A, Georgiou A, Wong YNS, Smith M, Strauss D, Hayes A, Nicol D, O'Brien T, Mårtensson L, Ljungars A, Teige I, Frendéus B; TRACERx Melanoma; TRACERx Renal; TRACERx Lung consortia; Pule M, Marafioti T, Gore M, Larkin J, Turajlic S, Swanton C, Peggs KS, Quezada SA. Arce Vargas F, et al. Cancer Cell. 2018 Apr 9;33(4):649-663.e4. doi: 10.1016/j.ccell.2018.02.010. Epub 2018 Mar 22. Cancer Cell. 2018. PMID: 29576375 Free PMC article.
A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote migration of lung cancer cells.
Ginn L, Maltas J, Baker MJ, Chaturvedi A, Wilson L, Guilbert R, Amaral FMR, Priest L, Mole H, Blackhall F, Diamantopoulou Z, Somervaille TCP, Hurlstone A, Malliri A. Ginn L, et al. Proc Natl Acad Sci U S A. 2023 Oct 3;120(40):e2300489120. doi: 10.1073/pnas.2300489120. Epub 2023 Sep 25. Proc Natl Acad Sci U S A. 2023. PMID: 37748077 Free PMC article.
Expanding Therapeutic Opportunities for Extrapulmonary Neuroendocrine Carcinoma.
Frizziero M, Kilgour E, Simpson KL, Rothwell DG, Moore DA, Frese KK, Galvin M, Lamarca A, Hubner RA, Valle JW, McNamara MG, Dive C. Frizziero M, et al. Clin Cancer Res. 2022 May 13;28(10):1999-2019. doi: 10.1158/1078-0432.CCR-21-3058. Clin Cancer Res. 2022. PMID: 35091446 Free PMC article. Review.
Direct Ras G12C inhibitors: crossing the rubicon.
Lindsay CR, Blackhall FH. Lindsay CR, et al. Br J Cancer. 2019 Jul;121(3):197-198. doi: 10.1038/s41416-019-0499-1. Epub 2019 Jun 26. Br J Cancer. 2019. PMID: 31239544 Free PMC article.
Mechanisms of Resistance to KRASG12C Inhibitors.
Dunnett-Kane V, Nicola P, Blackhall F, Lindsay C. Dunnett-Kane V, et al. Cancers (Basel). 2021 Jan 5;13(1):151. doi: 10.3390/cancers13010151. Cancers (Basel). 2021. PMID: 33466360 Free PMC article. Review.
A KRAS-responsive long non-coding RNA controls microRNA processing.
Shi L, Magee P, Fassan M, Sahoo S, Leong HS, Lee D, Sellers R, Brullé-Soumaré L, Cairo S, Monteverde T, Volinia S, Smith DD, Di Leva G, Galuppini F, Paliouras AR, Zeng K, O'Keefe R, Garofalo M. Shi L, et al. Nat Commun. 2021 Apr 1;12(1):2038. doi: 10.1038/s41467-021-22337-3. Nat Commun. 2021. PMID: 33795683 Free PMC article.
A biobank of small cell lung cancer CDX models elucidates inter- and intratumoral phenotypic heterogeneity.
Simpson KL, Stoney R, Frese KK, Simms N, Rowe W, Pearce SP, Humphrey S, Booth L, Morgan D, Dynowski M, Trapani F, Catozzi A, Revill M, Helps T, Galvin M, Girard L, Nonaka D, Carter L, Krebs MG, Cook N, Carter M, Priest L, Kerr A, Gazdar AF, Blackhall F, Dive C. Simpson KL, et al. Nat Cancer. 2020 Apr;1(4):437-451. doi: 10.1038/s43018-020-0046-2. Epub 2020 Apr 13. Nat Cancer. 2020. PMID: 35121965
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