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Page 1
Macrophage-derived glutamine boosts satellite cells and muscle regeneration.
Shang M, Cappellesso F, Amorim R, Serneels J, Virga F, Eelen G, Carobbio S, Rincon MY, Maechler P, De Bock K, Ho PC, Sandri M, Ghesquière B, Carmeliet P, Di Matteo M, Berardi E, Mazzone M. Shang M, et al. Nature. 2020 Nov;587(7835):626-631. doi: 10.1038/s41586-020-2857-9. Epub 2020 Oct 28. Nature. 2020. PMID: 33116312 Free PMC article.
Targeting the bicarbonate transporter SLC4A4 overcomes immunosuppression and immunotherapy resistance in pancreatic cancer.
Cappellesso F, Orban MP, Shirgaonkar N, Berardi E, Serneels J, Neveu MA, Di Molfetta D, Piccapane F, Caroppo R, Debellis L, Ostyn T, Joudiou N, Mignion L, Richiardone E, Jordan BF, Gallez B, Corbet C, Roskams T, DasGupta R, Tejpar S, Di Matteo M, Taverna D, Reshkin SJ, Topal B, Virga F, Mazzone M. Cappellesso F, et al. Nat Cancer. 2022 Dec;3(12):1464-1483. doi: 10.1038/s43018-022-00470-2. Epub 2022 Dec 15. Nat Cancer. 2022. PMID: 36522548 Free PMC article.
A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling.
Altea-Manzano P, Doglioni G, Liu Y, Cuadros AM, Nolan E, Fernández-García J, Wu Q, Planque M, Laue KJ, Cidre-Aranaz F, Liu XZ, Marin-Bejar O, Van Elsen J, Vermeire I, Broekaert D, Demeyer S, Spotbeen X, Idkowiak J, Montagne A, Demicco M, Alkan HF, Rabas N, Riera-Domingo C, Richard F, Geukens T, De Schepper M, Leduc S, Hatse S, Lambrechts Y, Kay EJ, Lilla S, Alekseenko A, Geldhof V, Boeckx B, de la Calle Arregui C, Floris G, Swinnen JV, Marine JC, Lambrechts D, Pelechano V, Mazzone M, Zanivan S, Cools J, Wildiers H, Baud V, Grünewald TGP, Ben-David U, Desmedt C, Malanchi I, Fendt SM. Altea-Manzano P, et al. Nat Cancer. 2023 Mar;4(3):344-364. doi: 10.1038/s43018-023-00513-2. Epub 2023 Feb 2. Nat Cancer. 2023. PMID: 36732635 Free PMC article.
Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix.
Kay EJ, Paterson K, Riera-Domingo C, Sumpton D, Däbritz JHM, Tardito S, Boldrini C, Hernandez-Fernaud JR, Athineos D, Dhayade S, Stepanova E, Gjerga E, Neilson LJ, Lilla S, Hedley A, Koulouras G, McGregor G, Jamieson C, Johnson RM, Park M, Kirschner K, Miller C, Kamphorst JJ, Loayza-Puch F, Saez-Rodriguez J, Mazzone M, Blyth K, Zagnoni M, Zanivan S. Kay EJ, et al. Nat Metab. 2022 Jun;4(6):693-710. doi: 10.1038/s42255-022-00582-0. Epub 2022 Jun 27. Nat Metab. 2022. PMID: 35760868 Free PMC article.
Podoplanin-Expressing Macrophages Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer.
Bieniasz-Krzywiec P, Martín-Pérez R, Ehling M, García-Caballero M, Pinioti S, Pretto S, Kroes R, Aldeni C, Di Matteo M, Prenen H, Tribulatti MV, Campetella O, Smeets A, Noel A, Floris G, Van Ginderachter JA, Mazzone M. Bieniasz-Krzywiec P, et al. Cell Metab. 2019 Nov 5;30(5):917-936.e10. doi: 10.1016/j.cmet.2019.07.015. Epub 2019 Aug 22. Cell Metab. 2019. PMID: 31447322 Free PMC article.
Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding.
Riera-Domingo C, Leite-Gomes E, Charatsidou I, Zhao P, Carrá G, Cappellesso F, Mourao L, De Schepper M, Liu D, Serneels J, Alameh MG, Shuvaev VV, Geukens T, Isnaldi E, Prenen H, Weissman D, Muzykantov VR, Soenen S, Desmedt C, Scheele CLGJ, Sablina A, Di Matteo M, Martín-Pérez R, Mazzone M. Riera-Domingo C, et al. Sci Adv. 2023 Mar 22;9(12):eadd5028. doi: 10.1126/sciadv.add5028. Epub 2023 Mar 22. Sci Adv. 2023. PMID: 36947620 Free PMC article.
Stroma-derived miR-214 coordinates tumor dissemination.
Orso F, Virga F, Dettori D, Dalmasso A, Paradzik M, Savino A, Pomatto MAC, Quirico L, Cucinelli S, Coco M, Mareschi K, Fagioli F, Salmena L, Camussi G, Provero P, Poli V, Mazzone M, Pandolfi PP, Taverna D. Orso F, et al. J Exp Clin Cancer Res. 2023 Jan 13;42(1):20. doi: 10.1186/s13046-022-02553-5. J Exp Clin Cancer Res. 2023. PMID: 36639824 Free PMC article.
A Metabolic Gene Survey Pinpoints Fucosylation as a Key Pathway Underlying the Suppressive Function of Regulatory T Cells in Cancer.
Pinioti S, Sharma H, Flerin NC, Yu Q, Tzoumpa A, Trusso Cafarello S, De Bousser E, Callewaert N, Oldenhove G, Schlenner S, Thienpont B, Garg AD, Di Matteo M, Mazzone M. Pinioti S, et al. Cancer Immunol Res. 2023 Dec 1;11(12):1611-1629. doi: 10.1158/2326-6066.CIR-22-0606. Cancer Immunol Res. 2023. PMID: 37933083 Free PMC article.
Plexin-A4 Mediates Cytotoxic T-cell Trafficking and Exclusion in Cancer.
Celus W, Oliveira AI, Rivis S, Van Acker HH, Landeloos E, Serneels J, Cafarello ST, Van Herck Y, Mastrantonio R, Köhler A, Garg AD, Flamand V, Tamagnone L, Marine JC, Di Matteo M, Costa BM, Bechter O, Mazzone M. Celus W, et al. Cancer Immunol Res. 2022 Jan;10(1):126-141. doi: 10.1158/2326-6066.CIR-21-0061. Epub 2021 Nov 23. Cancer Immunol Res. 2022. PMID: 34815265 Free PMC article.
20 results