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Pharmacogenetic association of the angiotensin-converting enzyme insertion/deletion polymorphism on blood pressure and cardiovascular risk in relation to antihypertensive treatment: the Genetics of Hypertension-Associated Treatment (GenHAT) study.
Arnett DK, Davis BR, Ford CE, Boerwinkle E, Leiendecker-Foster C, Miller MB, Black H, Eckfeldt JH. Arnett DK, et al. Circulation. 2005 Jun 28;111(25):3374-83. doi: 10.1161/CIRCULATIONAHA.104.504639. Epub 2005 Jun 20. Circulation. 2005. PMID: 15967849 Clinical Trial.
Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium.
Bis JC, Sitlani C, Irvin R, Avery CL, Smith AV, Sun F, Evans DS, Musani SK, Li X, Trompet S, Krijthe BP, Harris TB, Quibrera PM, Brody JA, Demissie S, Davis BR, Wiggins KL, Tranah GJ, Lange LA, Sotoodehnia N, Stott DJ, Franco OH, Launer LJ, Stürmer T, Taylor KD, Cupples LA, Eckfeldt JH, Smith NL, Liu Y, Wilson JG, Heckbert SR, Buckley BM, Ikram MA, Boerwinkle E, Chen YD, de Craen AJ, Uitterlinden AG, Rotter JI, Ford I, Hofman A, Sattar N, Slagboom PE, Westendorp RG, Gudnason V, Vasan RS, Lumley T, Cummings SR, Taylor HA Jr, Post W, Jukema JW, Stricker BH, Whitsel EA, Psaty BM, Arnett D. Bis JC, et al. PLoS One. 2015 Oct 30;10(10):e0140496. doi: 10.1371/journal.pone.0140496. eCollection 2015. PLoS One. 2015. PMID: 26516778 Free PMC article.
Interactions between the single nucleotide polymorphisms in the homocysteine pathway (MTHFR 677C>T, MTHFR 1298 A>C, and CBSins) and the efficacy of HMG-CoA reductase inhibitors in preventing cardiovascular disease in high-risk patients of hypertension: the GenHAT study.
Maitland-van der Zee AH, Lynch A, Boerwinkle E, Arnett DK, Davis BR, Leiendecker-Foster C, Ford CE, Eckfeldt JH. Maitland-van der Zee AH, et al. Pharmacogenet Genomics. 2008 Aug;18(8):651-6. doi: 10.1097/FPC.0b013e3282fe1759. Pharmacogenet Genomics. 2008. PMID: 18622257 Free PMC article. Clinical Trial.
The effect of nine common polymorphisms in coagulation factor genes (F2, F5, F7, F12 and F13 ) on the effectiveness of statins: the GenHAT study.
Maitland-van der Zee AH, Peters BJ, Lynch AI, Boerwinkle E, Arnett DK, Cheng S, Davis BR, Leiendecker-Foster C, Ford CE, Eckfeldt JH. Maitland-van der Zee AH, et al. Pharmacogenet Genomics. 2009 May;19(5):338-44. doi: 10.1097/fpc.0b013e32832933b7. Pharmacogenet Genomics. 2009. PMID: 19415820 Free PMC article. Clinical Trial.