210904/WT_/Wellcome Trust/United Kingdom[Grants and Funding] - Search Results

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Year	Number of Results
2019	1
2020	3
2025	0

Page 1

Novel HDAC6 Inhibitors Increase Tubulin Acetylation and Rescue Axonal Transport of Mitochondria in a Model of Charcot-Marie-Tooth Type 2F.

Adalbert R, Kaieda A, Antoniou C, Loreto A, Yang X, Gilley J, Hoshino T, Uga K, Makhija MT, Coleman MP. Adalbert R, et al. ACS Chem Neurosci. 2020 Feb 5;11(3):258-267. doi: 10.1021/acschemneuro.9b00338. Epub 2020 Jan 8. ACS Chem Neurosci. 2020. PMID: 31845794 Free PMC article.

Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity.

Mabbitt PD, Loreto A, Déry MA, Fletcher AJ, Stanley M, Pao KC, Wood NT, Coleman MP, Virdee S. Mabbitt PD, et al. Nat Chem Biol. 2020 Nov;16(11):1227-1236. doi: 10.1038/s41589-020-0598-6. Epub 2020 Aug 3. Nat Chem Biol. 2020. PMID: 32747811 Free PMC article.

Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration.

Loreto A, Hill CS, Hewitt VL, Orsomando G, Angeletti C, Gilley J, Lucci C, Sanchez-Martinez A, Whitworth AJ, Conforti L, Dajas-Bailador F, Coleman MP. Loreto A, et al. Neurobiol Dis. 2020 Feb;134:104678. doi: 10.1016/j.nbd.2019.104678. Epub 2019 Nov 15. Neurobiol Dis. 2020. PMID: 31740269 Free PMC article.

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