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Boosting the catalytic efficiency of UGT51 for efficient production of rare ginsenoside Rh2.
Ali MY, Abdalla M, Roumia AF, Tammam MA, Ramadan MF, Edrees MAH, Kabra A, Zhu D. Ali MY, et al. Folia Microbiol (Praha). 2025 Jan 22. doi: 10.1007/s12223-025-01241-z. Online ahead of print. Folia Microbiol (Praha). 2025. PMID: 39841376
To this end, we employed site-directed mutagenesis on UGT51 to improve its catalytic efficiency for enhanced production of ginsenoside Rh2. The mutated structure, featuring four key mutations (E805A, S998A, R1031A, and L1032A), exhibited heightened stability, binding affin …
To this end, we employed site-directed mutagenesis on UGT51 to improve its catalytic efficiency for enhanced production of ginsenoside Rh2. …