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Single-cell multi-omics profiling reveals key regulatory mechanisms that poise germinal vesicle oocytes for maturation in pigs.
Yuan X, Chen N, Feng Y, Li N, Pan X, Tian Y, Wang J, Jiang Y, He D, Li J, Gao F. Yuan X, et al. Cell Mol Life Sci. 2023 Jul 22;80(8):222. doi: 10.1007/s00018-023-04873-x. Cell Mol Life Sci. 2023. PMID: 37480402 Free PMC article.
We further confirmed Insulin Receptor Substrate-1 in insulin signaling pathway is a key regulator on maturation by in vitro maturation experiments. Our study provides new insights into the regulatory mechanisms between meiotic arrest and meiotic resumption in mammalian ooc …
We further confirmed Insulin Receptor Substrate-1 in insulin signaling pathway is a key regulator on maturation by in vitro maturatio …
Integrated Single-Trait and Multi-Trait GWASs Reveal the Genetic Architecture of Internal Organ Weight in Pigs.
Li X, Wu J, Zhuang Z, Ye Y, Zhou S, Qiu Y, Ruan D, Wang S, Yang J, Wu Z, Cai G, Zheng E. Li X, et al. Animals (Basel). 2023 Feb 23;13(5):808. doi: 10.3390/ani13050808. Animals (Basel). 2023. PMID: 36899665 Free PMC article.
In conclusion, our exploration of the genetic architecture of internal organ weights helps us better understand growth traits, and the key SNPs identified could play a potential role in animal breeding programs....
In conclusion, our exploration of the genetic architecture of internal organ weights helps us better understand growth traits, and the ke …
Genome-wide association study for loin muscle area of commercial crossbred pigs.
Luan M, Ruan D, Qiu Y, Ye Y, Zhou S, Yang J, Sun Y, Ma F, Wu Z, Yang J, Yang M, Zheng E, Cai G, Huang S. Luan M, et al. Anim Biosci. 2023 Jun;36(6):861-868. doi: 10.5713/ab.22.0407. Epub 2023 Jan 11. Anim Biosci. 2023. PMID: 36634654 Free PMC article.
RESULTS: After quality control, we detected 35,426 SNPs, including six SNPs significantly associated with LMA in pigs, with MARC0094338 and ASGA0072817 being the two key SNPs responsible for 1.77% and 2.48% of the phenotypic variance of LMA, respectively. ...
RESULTS: After quality control, we detected 35,426 SNPs, including six SNPs significantly associated with LMA in pigs, with MARC0094338 and …
Comprehensive Analysis of Placental DNA Methylation Changes and Fetal Birth Weight in Pigs.
Tan B, Xiao L, Wang Y, Zhou C, Huang H, Li Z, Hong L, Cai G, Wu Z, Gu T. Tan B, et al. Int J Mol Sci. 2024 Jul 13;25(14):7702. doi: 10.3390/ijms25147702. Int J Mol Sci. 2024. PMID: 39062945 Free PMC article.
The transcriptome analysis identified 1682 differential expressed genes and revealed key transcriptional properties in distinct placentas. We also identified key transcription factors that may drive the differences in DNA methylome patterns between placentas. ...
The transcriptome analysis identified 1682 differential expressed genes and revealed key transcriptional properties in distinct place …
14 results