ALKBH5 regulates chicken adipogenesis by mediating LCAT mRNA stability depending on m6A modification.
Chao X, Guo L, Ye C, Liu A, Wang X, Ye M, Fan Z, Luan K, Chen J, Zhang C, Liu M, Zhou B, Zhang X, Li Z, Luo Q.
Chao X, et al.
BMC Genomics. 2024 Jun 25;25(1):634. doi: 10.1186/s12864-024-10537-2.
BMC Genomics. 2024.
PMID: 38918701
Free PMC article.
In addition, LCAT inhibits preadipocyte proliferation and promotes preadipocyte differentiation, and plays a key role in adipogenesis. CONCLUSIONS: In conclusion, ALKBH5 mediates RNA stability of LCAT through demethylation and affects chicken adipogenesis. ...
In addition, LCAT inhibits preadipocyte proliferation and promotes preadipocyte differentiation, and plays a key role in adipogenesis …