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De novo synthesis of nervonic acid and optimization of metabolic regulation by Yarrowia lipolytica.
Bioresour Bioprocess. 2023 Oct 6;10(1):70. doi: 10.1186/s40643-023-00689-6.
Bioresour Bioprocess. 2023.
PMID: 38647797
Free PMC article.
Two strategies to improve the supply of PKS extender units for ansamitocin P-3 biosynthesis by CRISPR-Cas9.
Guo S, Sun X, Li R, Zhang T, Hu F, Liu F, Hua Q.
Guo S, et al.
Bioresour Bioprocess. 2022 Aug 29;9(1):90. doi: 10.1186/s40643-022-00583-7.
Bioresour Bioprocess. 2022.
PMID: 38647752
Free PMC article.
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Synthesis of β-ionone from xylose and lignocellulosic hydrolysate in genetically engineered oleaginous yeast Yarrowia lipolytica.
Shi JT, Wu YY, Sun RZ, Hua Q, Wei LJ.
Shi JT, et al.
Biotechnol Lett. 2024 Dec;46(6):1219-1236. doi: 10.1007/s10529-024-03534-8. Epub 2024 Oct 8.
Biotechnol Lett. 2024.
PMID: 39377872
Second, to further develop a high-level production strain for beta-ionone, we optimized key genes in the mevalonate pathway by multi-round iterative transformations mediated by non-homologous end joining, combined with a protein tagging strategy. ...
Second, to further develop a high-level production strain for beta-ionone, we optimized key genes in the mevalonate pathway by multi- …
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