Characterization of a selective, iron-chelating antifungal compound that disrupts fungal metabolism and synergizes with fluconazole.
Corrales J, Ramos-Alonso L, González-Sabín J, Ríos-Lombardía N, Trevijano-Contador N, Engen Berg H, Sved Skottvoll F, Moris F, Zaragoza O, Chymkowitch P, Garcia I, Enserink JM.
Corrales J, et al.
Microbiol Spectr. 2024 Feb 6;12(2):e0259423. doi: 10.1128/spectrum.02594-23. Epub 2024 Jan 17.
Microbiol Spectr. 2024.
PMID: 38230926
Free PMC article.
Fungal infections are a growing global health concern due to the limited number of available antifungal therapies as well as the emergence of fungi that are resistant to first-line antimicrobials, particularly azoles and echinocandins. ...
Fungal infections are a growing global health concern due to the limited number of available antifungal therapies as well as the emer …