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Suppression of non-small-cell lung cancer A549 tumor growth by an mtDNA mutation-targeting pyrrole-imidazole polyamide-triphenylphosphonium and a senolytic drug.
Cancer Sci. 2022 Apr;113(4):1321-1337. doi: 10.1111/cas.15290. Epub 2022 Feb 16.
Cancer Sci. 2022.
PMID: 35112436
Free PMC article.
A PI polyamide-TPP conjugate targeting a mtDNA mutation induces cell death of cancer cells with the mutation.
Koshikawa N, Yasui N, Kida Y, Shinozaki Y, Tsuji K, Watanabe T, Takenaga K, Nagase H.
Koshikawa N, et al.
Cancer Sci. 2021 Jun;112(6):2504-2512. doi: 10.1111/cas.14912. Epub 2021 May 2.
Cancer Sci. 2021.
PMID: 33811417
Free PMC article.
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