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The regulation and functions of DNA and RNA G-quadruplexes.
Varshney D, Spiegel J, Zyner K, Tannahill D, Balasubramanian S. Varshney D, et al. Nat Rev Mol Cell Biol. 2020 Aug;21(8):459-474. doi: 10.1038/s41580-020-0236-x. Epub 2020 Apr 20. Nat Rev Mol Cell Biol. 2020. PMID: 32313204 Free PMC article. Review.
G-quadruplex structures mark human regulatory chromatin.
Hänsel-Hertsch R, Beraldi D, Lensing SV, Marsico G, Zyner K, Parry A, Di Antonio M, Pike J, Kimura H, Narita M, Tannahill D, Balasubramanian S. Hänsel-Hertsch R, et al. Nat Genet. 2016 Oct;48(10):1267-72. doi: 10.1038/ng.3662. Epub 2016 Sep 12. Nat Genet. 2016. PMID: 27618450
The Structure and Function of DNA G-Quadruplexes.
Spiegel J, Adhikari S, Balasubramanian S. Spiegel J, et al. Trends Chem. 2020 Feb;2(2):123-136. doi: 10.1016/j.trechm.2019.07.002. Trends Chem. 2020. PMID: 32923997 Free PMC article. Review.
Genetic interactions of G-quadruplexes in humans.
Zyner KG, Mulhearn DS, Adhikari S, Martínez Cuesta S, Di Antonio M, Erard N, Hannon GJ, Tannahill D, Balasubramanian S. Zyner KG, et al. Elife. 2019 Jul 9;8:e46793. doi: 10.7554/eLife.46793. Elife. 2019. PMID: 31287417 Free PMC article.
Natural, modified DNA bases.
Bilyard MK, Becker S, Balasubramanian S. Bilyard MK, et al. Curr Opin Chem Biol. 2020 Aug;57:1-7. doi: 10.1016/j.cbpa.2020.01.014. Epub 2020 Mar 4. Curr Opin Chem Biol. 2020. PMID: 32145439 Free article. Review.
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.
Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O'Neil NJ, Santos ND, Silvester J, Wei V, Garcia J, Kabeer F, Lai D, Soriano P, Banáth J, Chiu DS, Yap D, Le DD, Ye FB, Zhang A, Thu K, Soong J, Lin SC, Tsai AH, Osako T, Algara T, Saunders DN, Wong J, Xian J, Bally MB, Brenton JD, Brown GW, Shah SP, Cescon D, Mak TW, Caldas C, Stirling PC, Hieter P, Balasubramanian S, Aparicio S. Xu H, et al. Nat Commun. 2017 Feb 17;8:14432. doi: 10.1038/ncomms14432. Nat Commun. 2017. PMID: 28211448 Free PMC article.
Landscape of G-quadruplex DNA structural regions in breast cancer.
Hänsel-Hertsch R, Simeone A, Shea A, Hui WWI, Zyner KG, Marsico G, Rueda OM, Bruna A, Martin A, Zhang X, Adhikari S, Tannahill D, Caldas C, Balasubramanian S. Hänsel-Hertsch R, et al. Nat Genet. 2020 Sep;52(9):878-883. doi: 10.1038/s41588-020-0672-8. Epub 2020 Aug 3. Nat Genet. 2020. PMID: 32747825
35 results