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Page 1
Piezo1 Inactivation in Chondrocytes Impairs Trabecular Bone Formation.
Hendrickx G, Fischer V, Liedert A, von Kroge S, Haffner-Luntzer M, Brylka L, Pawlus E, Schweizer M, Yorgan T, Baranowsky A, Rolvien T, Neven M, Schumacher U, Beech DJ, Amling M, Ignatius A, Schinke T. Hendrickx G, et al. J Bone Miner Res. 2021 Feb;36(2):369-384. doi: 10.1002/jbmr.4198. Epub 2020 Nov 12. J Bone Miner Res. 2021. PMID: 33180356 Free article.
Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels.
Shi J, Hyman AJ, De Vecchis D, Chong J, Lichtenstein L, Futers TS, Rouahi M, Salvayre AN, Auge N, Kalli AC, Beech DJ. Shi J, et al. Cell Rep. 2020 Oct 6;33(1):108225. doi: 10.1016/j.celrep.2020.108225. Cell Rep. 2020. PMID: 33027663 Free PMC article.
RNA and the PIEZO force sensor.
Beech DJ, Lichtenstein L. Beech DJ, et al. Cell Res. 2020 Oct;30(10):829-830. doi: 10.1038/s41422-020-00413-5. Cell Res. 2020. PMID: 32884138 Free PMC article. No abstract available.
Pharmacology of PIEZO1 channels.
Kinsella JA, Debant M, Parsonage G, Morley LC, Bajarwan M, Revill C, Foster R, Beech DJ. Kinsella JA, et al. Br J Pharmacol. 2024 Dec;181(23):4714-4732. doi: 10.1111/bph.17351. Epub 2024 Oct 14. Br J Pharmacol. 2024. PMID: 39402010 Review.
Biological Effects of Modifications of the Englerin A Glycolate.
Seenadera SPD, Long SA, Akee R, Bermudez G, Parsonage G, Strope J, Peer C, Figg WD, Parker KA, Beech DJ, Beutler JA. Seenadera SPD, et al. ACS Med Chem Lett. 2022 Aug 22;13(9):1472-1476. doi: 10.1021/acsmedchemlett.2c00258. eCollection 2022 Sep 8. ACS Med Chem Lett. 2022. PMID: 36105325 Free PMC article.
Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress.
Endesh N, Chuntharpursat-Bon E, Revill C, Yuldasheva NY, Futers TS, Parsonage G, Humphreys N, Adamson A, Morley LC, Cubbon RM, Prasad KR, Foster R, Lichtenstein L, Beech DJ. Endesh N, et al. Liver Int. 2023 Sep;43(9):2026-2038. doi: 10.1111/liv.15646. Epub 2023 Jun 22. Liver Int. 2023. PMID: 37349903 Free PMC article.
Improved PIEZO1 agonism through 4-benzoic acid modification of Yoda1.
Parsonage G, Cuthbertson K, Endesh N, Murciano N, Hyman AJ, Revill CH, Povstyan OV, Chuntharpursat-Bon E, Debant M, Ludlow MJ, Futers TS, Lichtenstein L, Kinsella JA, Bartoli F, Rotordam MG, Becker N, Brüggemann A, Foster R, Beech DJ. Parsonage G, et al. Br J Pharmacol. 2023 Aug;180(16):2039-2063. doi: 10.1111/bph.15996. Epub 2023 Jan 31. Br J Pharmacol. 2023. PMID: 36457143 Free PMC article.
PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing.
Chuntharpursat-Bon E, Povstyan OV, Ludlow MJ, Carrier DJ, Debant M, Shi J, Gaunt HJ, Bauer CC, Curd A, Simon Futers T, Baxter PD, Peckham M, Muench SP, Adamson A, Humphreys N, Tumova S, Bon RS, Cubbon R, Lichtenstein L, Beech DJ. Chuntharpursat-Bon E, et al. Commun Biol. 2023 Apr 1;6(1):358. doi: 10.1038/s42003-023-04706-4. Commun Biol. 2023. PMID: 37005489 Free PMC article.
25 results