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Quadrupling Inhaled Glucocorticoid Dose to Abort Asthma Exacerbations.
McKeever T, Mortimer K, Wilson A, Walker S, Brightling C, Skeggs A, Pavord I, Price D, Duley L, Thomas M, Bradshaw L, Higgins B, Haydock R, Mitchell E, Devereux G, Harrison T. McKeever T, et al. N Engl J Med. 2018 Mar 8;378(10):902-910. doi: 10.1056/NEJMoa1714257. Epub 2018 Mar 3. N Engl J Med. 2018. PMID: 29504499 Free article. Clinical Trial.
Temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations: FAST.
McKeever T, Mortimer K, Bradshaw L, Haydock R, Pavord I, Higgins B, Walker S, Wilson A, Price D, Thomas M, Devereux G, Brightling C, Renwick C, Parrott S, Mitchell E, Duley L, Harrison T. McKeever T, et al. Health Technol Assess. 2018 Dec;22(70):1-82. doi: 10.3310/hta22700. Health Technol Assess. 2018. PMID: 30520413 Free PMC article. Clinical Trial.
FourFold Asthma Study (FAST): a study protocol for a randomised controlled trial evaluating the clinical cost-effectiveness of temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations.
Skeggs A, McKeever T, Duley L, Mitchell E, Bradshaw L, Mortimer K, Walker S, Parrott S, Wilson A, Pavord I, Brightling C, Thomas M, Price D, Devereux G, Higgins B, Harrison T, Haydock R. Skeggs A, et al. Trials. 2016 Oct 13;17(1):499. doi: 10.1186/s13063-016-1608-6. Trials. 2016. PMID: 27737713 Free PMC article. Clinical Trial.