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Comprehensive analysis of transcriptional promoter structure and function in 1% of the human genome.
Cooper SJ, Trinklein ND, Anton ED, Nguyen L, Myers RM. Cooper SJ, et al. Genome Res. 2006 Jan;16(1):1-10. doi: 10.1101/gr.4222606. Epub 2005 Dec 12. Genome Res. 2006. PMID: 16344566 Free PMC article.
Using full-length cDNA sequences to identify transcription start sites (TSS), we predicted more than 900 putative human transcriptional promoters in the ENCODE regions, representing a comprehensive sampling of promoters in 1% of the genome. We identified 387 fragments that …
Using full-length cDNA sequences to identify transcription start sites (TSS), we predicted more than 900 putative human transcriptional prom …
Serum response factor binding sites differ in three human cell types.
Cooper SJ, Trinklein ND, Nguyen L, Myers RM. Cooper SJ, et al. Genome Res. 2007 Feb;17(2):136-44. doi: 10.1101/gr.5875007. Epub 2007 Jan 2. Genome Res. 2007. PMID: 17200232 Free PMC article.
Although we did not see a strong correlation between SRF binding and epigenetics modifications, at these sites, we propose that SRF cofactors may play an important role in determining cell-dependent SRF binding sites. ELK4 (previously known as SAP-1 [SRF-associated protein …
Although we did not see a strong correlation between SRF binding and epigenetics modifications, at these sites, we propose that SRF cofactor …