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Investigating the dynamic nature of the ABC transporters: ABCB1 and MsbA as examples for the potential synergies of MD theory and EPR applications.
Biochem Soc Trans. 2015 Oct;43(5):1023-32. doi: 10.1042/BST20150138.
Biochem Soc Trans. 2015.
PMID: 26517918
Review.
The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis.
van Wonderen JH, McMahon RM, O'Mara ML, McDevitt CA, Thomson AJ, Kerr ID, MacMillan F, Callaghan R.
van Wonderen JH, et al.
FEBS J. 2014 May;281(9):2190-2201. doi: 10.1111/febs.12773. Epub 2014 Apr 1.
FEBS J. 2014.
PMID: 24597976
Free PMC article.
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