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19 results

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Page 1
Genomically humanized mice: technologies and promises.
Devoy A, Bunton-Stasyshyn RK, Tybulewicz VL, Smith AJ, Fisher EM. Devoy A, et al. Nat Rev Genet. 2011 Dec 16;13(1):14-20. doi: 10.1038/nrg3116. Nat Rev Genet. 2011. PMID: 22179716 Free PMC article. Review.
Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus.
Granno S, Nixon-Abell J, Berwick DC, Tosh J, Heaton G, Almudimeegh S, Nagda Z, Rain JC, Zanda M, Plagnol V, Tybulewicz VLJ, Cleverley K, Wiseman FK, Fisher EMC, Harvey K. Granno S, et al. Sci Rep. 2019 May 13;9(1):7322. doi: 10.1038/s41598-019-43820-4. Sci Rep. 2019. PMID: 31086297 Free PMC article.
Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes.
Lana-Elola E, Cater H, Watson-Scales S, Greenaway S, Müller-Winkler J, Gibbins D, Nemes M, Slender A, Hough T, Keskivali-Bond P, Scudamore CL, Herbert E, Banks GT, Mobbs H, Canonica T, Tosh J, Noy S, Llorian M, Nolan PM, Griffin JL, Good M, Simon M, Mallon AM, Wells S, Fisher EMC, Tybulewicz VLJ. Lana-Elola E, et al. Dis Model Mech. 2021 Oct 1;14(10):dmm049157. doi: 10.1242/dmm.049157. Epub 2021 Oct 15. Dis Model Mech. 2021. PMID: 34477842 Free PMC article.
Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration.
Watson-Scales S, Kalmar B, Lana-Elola E, Gibbins D, La Russa F, Wiseman F, Williamson M, Saccon R, Slender A, Olerinyova A, Mahmood R, Nye E, Cater H, Wells S, Yu YE, Bennett DLH, Greensmith L, Fisher EMC, Tybulewicz VLJ. Watson-Scales S, et al. PLoS Genet. 2018 May 10;14(5):e1007383. doi: 10.1371/journal.pgen.1007383. eCollection 2018 May. PLoS Genet. 2018. PMID: 29746474 Free PMC article.
Hippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome.
Witton J, Padmashri R, Zinyuk LE, Popov VI, Kraev I, Line SJ, Jensen TP, Tedoldi A, Cummings DM, Tybulewicz VLJ, Fisher EMC, Bannerman DM, Randall AD, Brown JT, Edwards FA, Rusakov DA, Stewart MG, Jones MW. Witton J, et al. Nat Neurosci. 2015 Sep;18(9):1291-1298. doi: 10.1038/nn.4072. Epub 2015 Aug 3. Nat Neurosci. 2015. PMID: 26237367 Free PMC article.
19 results