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Fibril fragmentation enhances amyloid cytotoxicity.
Xue WF, Hellewell AL, Gosal WS, Homans SW, Hewitt EW, Radford SE. Xue WF, et al. J Biol Chem. 2009 Dec 4;284(49):34272-82. doi: 10.1074/jbc.M109.049809. Epub 2009 Oct 6. J Biol Chem. 2009. PMID: 19808677 Free PMC article.
An in vivo platform for identifying inhibitors of protein aggregation.
Saunders JC, Young LM, Mahood RA, Jackson MP, Revill CH, Foster RJ, Smith DA, Ashcroft AE, Brockwell DJ, Radford SE. Saunders JC, et al. Nat Chem Biol. 2016 Feb;12(2):94-101. doi: 10.1038/nchembio.1988. Epub 2015 Dec 14. Nat Chem Biol. 2016. PMID: 26656088 Free PMC article.