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Page 1
Did you mean nmda mk (6,447 results)?
Bupropion and Naltrexone in Methamphetamine Use Disorder.
Trivedi MH, Walker R, Ling W, Dela Cruz A, Sharma G, Carmody T, Ghitza UE, Wahle A, Kim M, Shores-Wilson K, Sparenborg S, Coffin P, Schmitz J, Wiest K, Bart G, Sonne SC, Wakhlu S, Rush AJ, Nunes EV, Shoptaw S. Trivedi MH, et al. N Engl J Med. 2021 Jan 14;384(2):140-153. doi: 10.1056/NEJMoa2020214. N Engl J Med. 2021. PMID: 33497547 Free PMC article. Clinical Trial.
CONCLUSIONS: Among adults with methamphetamine use disorder, the response over a period of 12 weeks among participants who received extended-release injectable naltrexone plus oral extended-release bupropion was low but was higher than that among participants who received placebo …
CONCLUSIONS: Among adults with methamphetamine use disorder, the response over a period of 12 weeks among participants who received extended …
Child protection training for professionals to improve reporting of child abuse and neglect.
Walsh K, Eggins E, Hine L, Mathews B, Kenny MC, Howard S, Ayling N, Dallaston E, Pink E, Vagenas D. Walsh K, et al. Cochrane Database Syst Rev. 2022 Jul 5;7(7):CD011775. doi: 10.1002/14651858.CD011775.pub2. Cochrane Database Syst Rev. 2022. PMID: 35788913 Free PMC article. Review.
Ensuring they are trained in reporting child abuse and neglect is a key priority for nations and organisations if efforts to address violence against children are to succeed. ...Three studies measured the number of cases of child abuse and neglect via participants' …
Ensuring they are trained in reporting child abuse and neglect is a key priority for nations and organisations if efforts to address …
mGluR5 positive allosteric modulation prevents MK-801 induced increases in extracellular glutamate in the rat medial prefrontal cortex.
LaCrosse AL, May CE, Griffin WC, Olive MF. LaCrosse AL, et al. Neuroscience. 2024 Sep 13;555:83-91. doi: 10.1016/j.neuroscience.2024.06.016. Epub 2024 Jul 15. Neuroscience. 2024. PMID: 39019391
We therefore assessed the ability of the mGluR5 PAM, 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl) benzamide (CDPPB), to reduce elevated extracellular glutamate levels induced by the NMDAR antagonist, dizocilpine (MK-801), in the mPFC. Male Sprague-Dawley rats were implanted wi …
We therefore assessed the ability of the mGluR5 PAM, 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl) benzamide (CDPPB), to reduce elevated extracel …
Phencyclidine-induced behavioral sensitization.
Xu X, Domino EF. Xu X, et al. Pharmacol Biochem Behav. 1994 Mar;47(3):603-8. doi: 10.1016/0091-3057(94)90165-1. Pharmacol Biochem Behav. 1994. PMID: 8208780 Free article.
The present study reexamined the effects of the daily injection of phencyclidine on locomotor activity and stereotypy in rats, and investigated whether drug-environment conditioning was necessary for the development of behavioral sensitization and whether (5R,10S)-(+)-5-me …
The present study reexamined the effects of the daily injection of phencyclidine on locomotor activity and stereotypy in rats, and investiga …
Incidence of non-AIDS defining comorbidities among young adults with perinatally acquired HIV in North America.
Haw NJL, Lesko CR, Ng DK, Lam J, Lang R, Kitahata MM, Crane H, Eron J Jr, Gill MJ, Horberg MA, Karris M, Loutfy M, McGinnis KA, Moore RD, Althoff K, Agwu A; North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD). Haw NJL, et al. AIDS. 2024 Jul 15;38(9):1366-1374. doi: 10.1097/QAD.0000000000003892. Epub 2024 Mar 19. AIDS. 2024. PMID: 38507583
Changes in incidence of hepatitis C virus reinfection and access to direct-acting antiviral therapies in people with HIV from six countries, 2010-19: an analysis of data from a consortium of prospective cohort studies.
Sacks-Davis R, van Santen DK, Boyd A, Young J, Stewart A, Doyle JS, Rauch A, Mugglin C, Klein M, van der Valk M, Smit C, Jarrin I, Berenguer J, Lacombe K, Requena MB, Wittkop L, Leleux O, Bonnet F, Salmon D, Matthews GV, Guy R, Martin NK, Spelman T, Prins M, Stoove M, Hellard M; InCHEHC Collaboration. Sacks-Davis R, et al. Lancet HIV. 2024 Feb;11(2):e106-e116. doi: 10.1016/S2352-3018(23)00267-9. Epub 2024 Jan 12. Lancet HIV. 2024. PMID: 38224708
The proportion of incident HCV cases due to reinfection was highest during periods of broad access to direct-acting antivirals, highlighting the importance of reducing ongoing risks and continuing testing in people at risk. FUNDING: Australian National Health and Medical R …
The proportion of incident HCV cases due to reinfection was highest during periods of broad access to direct-acting antivirals, highlighting …
MK-801 inhibits L-DOPA-induced abnormal involuntary movements only at doses that worsen parkinsonism.
Paquette MA, Anderson AM, Lewis JR, Meshul CK, Johnson SW, Paul Berger S. Paquette MA, et al. Neuropharmacology. 2010 Jun;58(7):1002-8. doi: 10.1016/j.neuropharm.2010.01.003. Epub 2010 Jan 14. Neuropharmacology. 2010. PMID: 20079362 Free PMC article.
To test this hypothesis, we investigated MK-801, the most widely-studied NMDA antagonist. We found that chronic low-dose MK-801 (0.1 mg/kg) had no effect on development of AIMs or contraversive rotation. ...Conversely, higher doses of MK-801 (0.2-0.3 mg/kg) s …
To test this hypothesis, we investigated MK-801, the most widely-studied NMDA antagonist. We found that chronic low-dose MK-80 …
Drug discrimination studies with ibogaine.
Helsley S, Rabin RA, Winter JC. Helsley S, et al. Alkaloids Chem Biol. 2001;56:63-77. doi: 10.1016/s0099-9598(01)56008-3. Alkaloids Chem Biol. 2001. PMID: 11705117 Review.
In addition, opiate receptors may also be involved. In contrast, sigma 1, PCP/MK-801, 5-HT3, and 5-HT1A receptors do not appear to play a major role. Ibogaine's hallucinogenic effects may be explained by its interactions with 5-HT2A and 5-HT2C receptors, while its putative …
In addition, opiate receptors may also be involved. In contrast, sigma 1, PCP/MK-801, 5-HT3, and 5-HT1A receptors do not appear to pl …
Facilitators of and barriers to buprenorphine initiation in the emergency department: a scoping review.
Bozinoff N, Grennell E, Soobiah C, Farhan Z, Rodak T, Bucago C, Kingston K, Klaiman M, Poynter B, Shelton D, Schoenfeld E, Kalocsai C. Bozinoff N, et al. Lancet Reg Health Am. 2024 Sep 28;38:100899. doi: 10.1016/j.lana.2024.100899. eCollection 2024 Oct. Lancet Reg Health Am. 2024. PMID: 39381082 Free PMC article. Review.
Results demonstrate an immense effort across the U.S. and Canada to implement ED-initiated buprenorphine. Facilitators include multidisciplinary addiction teams and co-located, low-barrier, harm reduction-informed services to support transitions. ...Increased coordi …
Results demonstrate an immense effort across the U.S. and Canada to implement ED-initiated buprenorphine. Facilitators include …
Mouse behavioral endophenotypes for schizophrenia.
Amann LC, Gandal MJ, Halene TB, Ehrlichman RS, White SL, McCarren HS, Siegel SJ. Amann LC, et al. Brain Res Bull. 2010 Sep 30;83(3-4):147-61. doi: 10.1016/j.brainresbull.2010.04.008. Epub 2010 Apr 28. Brain Res Bull. 2010. PMID: 20433908 Review.
A variety of, pharmacological treatments, including ketamine, MK-801 and phencyclidine (PCP) can be used to, induce some of the deficits described above, and numerous transgenic mouse strains have been, developed to address the mechanisms responsible for such endophenotypi …
A variety of, pharmacological treatments, including ketamine, MK-801 and phencyclidine (PCP) can be used to, induce some of the defic …
719 results