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Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions.
Yvan-Charvet L, Welch C, Pagler TA, Ranalletta M, Lamkanfi M, Han S, Ishibashi M, Li R, Wang N, Tall AR. Yvan-Charvet L, et al. Among authors: welch c. Circulation. 2008 Oct 28;118(18):1837-47. doi: 10.1161/CIRCULATIONAHA.108.793869. Epub 2008 Oct 13. Circulation. 2008. PMID: 18852364 Free PMC article.
Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice.
Westerterp M, Murphy AJ, Wang M, Pagler TA, Vengrenyuk Y, Kappus MS, Gorman DJ, Nagareddy PR, Zhu X, Abramowicz S, Parks JS, Welch C, Fisher EA, Wang N, Yvan-Charvet L, Tall AR. Westerterp M, et al. Among authors: welch c. Circ Res. 2013 May 24;112(11):1456-65. doi: 10.1161/CIRCRESAHA.113.301086. Epub 2013 Apr 9. Circ Res. 2013. PMID: 23572498 Free PMC article.
Hypercholesterolemia and reduced HDL-C promote hematopoietic stem cell proliferation and monocytosis: studies in mice and FH children.
Tolani S, Pagler TA, Murphy AJ, Bochem AE, Abramowicz S, Welch C, Nagareddy PR, Holleran S, Hovingh GK, Kuivenhoven JA, Tall AR. Tolani S, et al. Among authors: welch c. Atherosclerosis. 2013 Jul;229(1):79-85. doi: 10.1016/j.atherosclerosis.2013.03.031. Epub 2013 Apr 19. Atherosclerosis. 2013. PMID: 23684512 Free PMC article. Clinical Trial.
LNK/SH2B3 Loss of Function Promotes Atherosclerosis and Thrombosis.
Wang W, Tang Y, Wang Y, Tascau L, Balcerek J, Tong W, Levine RL, Welch C, Tall AR, Wang N. Wang W, et al. Among authors: welch c. Circ Res. 2016 Sep 2;119(6):e91-e103. doi: 10.1161/CIRCRESAHA.116.308955. Epub 2016 Jul 18. Circ Res. 2016. PMID: 27430239 Free PMC article.
1,081 results