De Clercq E - Search Results

1

Treatment of visna virus infection in lambs with the acyclic nucleoside phosphonate analogue 9-(2-phosphonylmethoxyethyl)adenine (PMEA).

Thormar H, Georgsson G, Gunnarsson E, Naesens L, Torsteinsdóttir S, Balzarini J, De Clercq E. Thormar H, et al. Among authors: de clercq e. Antivir Chem Chemother. 1998 May;9(3):245-52. doi: 10.1177/095632029800900305. Antivir Chem Chemother. 1998. PMID: 9875403

2

Single-dose administration of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) and 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP) in the prophylaxis of retrovirus infection in vivo.

Naesens L, Balzarini J, De Clercq E. Naesens L, et al. Among authors: de clercq e. Antiviral Res. 1991 Jul;16(1):53-64. doi: 10.1016/0166-3542(91)90058-y. Antiviral Res. 1991. PMID: 1776876

3

Inhibition of visna virus replication and cytopathic effect in sheep choroid plexus cell cultures by selected anti-HIV agents.

Thormar H, Balzarini J, Debyser Z, Witvrouw M, Desmyter J, De Clercq E. Thormar H, et al. Among authors: de clercq e. Antiviral Res. 1995 May;27(1-2):49-57. doi: 10.1016/0166-3542(94)00082-j. Antiviral Res. 1995. PMID: 7486958

4

Inhibition of visna virus replication by 2',3'-dideoxynucleosides and acyclic nucleoside phosphonate analogs.

Thormar H, Balzarini J, Holy A, Jindrich J, Rosenberg I, Debyser Z, Desmyter J, De Clercq E. Thormar H, et al. Among authors: de clercq e. Antimicrob Agents Chemother. 1993 Dec;37(12):2540-4. doi: 10.1128/AAC.37.12.2540. Antimicrob Agents Chemother. 1993. PMID: 7509142 Free PMC article.

5

Inhibitory effect of 9-(2-phosphonylmethoxyethyl)adenine on visna virus infection in lambs: a model for in vivo testing of candidate anti-human immunodeficiency virus drugs.

Thormar H, Georgsson G, Pálsson PA, Balzarini J, Naesens L, Torsteinsdóttir S, De Clercq E. Thormar H, et al. Among authors: de clercq e. Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3283-7. doi: 10.1073/pnas.92.8.3283. Proc Natl Acad Sci U S A. 1995. PMID: 7724553 Free PMC article.

6

Pharmacokinetics in mice of the anti-retrovirus agent 9-(2-phosphonylmethoxyethyl)adenine.

Naesens L, Balzarini J, De Clercq E. Naesens L, et al. Among authors: de clercq e. Drug Metab Dispos. 1992 Sep-Oct;20(5):747-52. Drug Metab Dispos. 1992. PMID: 1358582

7

Acyclic adenine nucleoside phosphonates in plasma determined by high-performance liquid chromatography with fluorescence detection.

Naesens L, Balzarini J, De Clercq E. Naesens L, et al. Among authors: de clercq e. Clin Chem. 1992 Apr;38(4):480-5. Clin Chem. 1992. PMID: 1568310

8

Immunomodulatory activity of 9-(2-phosphonylmethoxyethyl)adenine (PMEA), a potent anti-HIV nucleotide analogue, on in vivo murine models.

Del Gobbo V, Foli A, Balzarini J, De Clercq E, Balestra E, Villani N, Marini S, Perno CF, Calio R. Del Gobbo V, et al. Among authors: de clercq e. Antiviral Res. 1991 Jul;16(1):65-75. doi: 10.1016/0166-3542(91)90059-z. Antiviral Res. 1991. PMID: 1723264

9

5-Phosphoribosyl 1-pyrophosphate synthetase converts the acyclic nucleoside phosphonates 9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine and 9-(2-phosphonylmethoxyethyl)adenine directly to their antivirally active diphosphate derivatives.

Balzarini J, De Clercq E. Balzarini J, et al. Among authors: de clercq e. J Biol Chem. 1991 May 15;266(14):8686-9. J Biol Chem. 1991. PMID: 1851154 Free article.

10

9-(2-Phosphonylmethoxyethyl)adenine (PMEA) effectively inhibits retrovirus replication in vitro and simian immunodeficiency virus infection in rhesus monkeys.

Balzarini J, Naesens L, Slachmuylders J, Niphuis H, Rosenberg I, Holý A, Schellekens H, De Clercq E. Balzarini J, et al. Among authors: de clercq e. AIDS. 1991 Jan;5(1):21-8. doi: 10.1097/00002030-199101000-00003. AIDS. 1991. PMID: 2059358

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

2,295 results

Search Page

Filters