Fujishima T - Search Results

1

A novel and practical route to A-ring enyne synthon for 1 alpha,25-dihydroxyvitamin D3 analogs: synthesis of A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D2 and 3-methyl-1,25-dihydroxyvitamin D3.

Konno K, Maki S, Fujishima T, Liu Z, Miura D, Chokki M, Takayama H. Konno K, et al. Among authors: fujishima t. Bioorg Med Chem Lett. 1998 Jan 20;8(2):151-6. doi: 10.1016/s0960-894x(97)10204-9. Bioorg Med Chem Lett. 1998. PMID: 9871644

2

Synthesis and testing of 2alpha-modified 1alpha,25-dihydroxyvitamin D(3) analogues with a double side chain: marked cell differentiation activity.

Suhara Y, Kittaka A, Kishimoto S, Calverley MJ, Fujishima T, Saito N, Sugiura T, Waku K, Takayama H. Suhara Y, et al. Among authors: fujishima t. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3255-8. doi: 10.1016/s0960-894x(02)00722-9. Bioorg Med Chem Lett. 2002. PMID: 12392726

3

Design and efficient synthesis of new stable 1alpha,25-dihydroxy-19-norvitamin D3 analogues containing amide bond.

Suhara Y, Kittaka A, Ono K, Kurihara M, Fujishima T, Yoshida A, Takayama H. Suhara Y, et al. Among authors: fujishima t. Bioorg Med Chem Lett. 2002 Dec 16;12(24):3533-6. doi: 10.1016/s0960-894x(02)00800-4. Bioorg Med Chem Lett. 2002. PMID: 12443770

4

Design, synthesis, and biological studies of the A-ring-modified 1,25-dihydroxyvitamin D3 analogs.

Takayama H, Kittaka A, Fujishima T, Suhara Y. Takayama H, et al. Among authors: fujishima t. Recent Results Cancer Res. 2003;164:289-317. doi: 10.1007/978-3-642-55580-0_21. Recent Results Cancer Res. 2003. PMID: 12899530 Review.

5

Design and synthesis of potent vitamin D receptor antagonists with A-ring modifications: remarkable effects of 2alpha-methyl introduction on antagonistic activity.

Fujishima T, Kojima Y, Azumaya I, Kittaka A, Takayama H. Fujishima T, et al. Bioorg Med Chem. 2003 Aug 15;11(17):3621-31. doi: 10.1016/s0968-0896(03)00371-7. Bioorg Med Chem. 2003. PMID: 12901907

6

Synthesis of 2,2-dimethyl-1,25-dihydroxyvitamin D3: A-ring structural motif that modulates interactions of vitamin D receptor with transcriptional coactivators.

Fujishima T, Kittaka A, Yamaoka K, Takeyama K, Kato S, Takayama H. Fujishima T, et al. Org Biomol Chem. 2003 Jun 7;1(11):1863-9. doi: 10.1039/b302017g. Org Biomol Chem. 2003. PMID: 12945766

7

Concise synthesis and biological activities of 2alpha-alkyl- and 2alpha-(omega-hydroxyalkyl)-20-epi-1alpha,25-dihydroxyvitamin D3.

Honzawa S, Suhara Y, Nihei K, Saito N, Kishimoto S, Fujishima T, Kurihara M, Sugiura T, Waku K, Takayama H, Kittaka A. Honzawa S, et al. Among authors: fujishima t. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3503-6. doi: 10.1016/s0960-894x(03)00739-x. Bioorg Med Chem Lett. 2003. PMID: 14505658

8

Synthesis and biological activity of 2-methyl-20-epi analogues of 1 alpha,25-dihydroxyvitamin D3.

Fujishima T, Liu Z, Miura D, Chokki M, Ishizuka S, Konno K, Takayama H. Fujishima T, et al. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2145-8. doi: 10.1016/s0960-894x(98)00363-1. Bioorg Med Chem Lett. 1998. PMID: 9873502

9

Novel ring A stereoisomers of 2-methyl-1alpha,25-dihydroxyvitamin D(3) and 2-methyl-20-epi-1alpha,25-dihydroxyvitamin D(3): transactivation of target genes and modulation of differentiation in human promyelocytic leukemia (HL-60) cells.

Nakagawa K, Kurobe M, Ozono K, Konno K, Fujishima T, Takayama H, Okano T. Nakagawa K, et al. Among authors: fujishima t. Biochem Pharmacol. 2000 Mar 15;59(6):691-702. doi: 10.1016/s0006-2952(99)00357-3. Biochem Pharmacol. 2000. PMID: 10677586

10

Syntheses and biological evaluation of novel 2alpha-substituted 1alpha,25-dihydroxyvitamin D3 analogues.

Suhara Y, Nihei KI, Tanigawa H, Fujishima T, Konno K, Nakagawa K, Okano T, Takayama H. Suhara Y, et al. Among authors: fujishima t. Bioorg Med Chem Lett. 2000 May 15;10(10):1129-32. doi: 10.1016/s0960-894x(00)00189-x. Bioorg Med Chem Lett. 2000. PMID: 10843234

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